SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3lr0 SENSOR PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ALA A  57
GLU A  77
LEU A  73
LEU A  69
 None
 0.97A 4iomA-3lr0A:
undetectable		 4iomA-3lr0A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3lr0 SENSOR PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 ALA A  57
GLU A  77
LEU A  73
LEU A  69
 None
 0.92A 4jjkA-3lr0A:
undetectable		 4jjkA-3lr0A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3lr0 SENSOR PROTEIN
(Burkholderia
pseudomallei) 		4 / 4 VAL A  79
LEU A  53
ASN A  76
ASP A  72
 None
 1.26A 5vcyA-3lr0A:
undetectable		 5vcyA-3lr0A:
19.42