SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 4 THR A 110
GLY A  94
ASP A  91
ALA A  98
 None
 1.20A 1sg9A-3lr1A:
undetectable		 1sg9A-3lr1A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 5 LEU A 108
PRO A  92
ALA A  93
ILE A  95
 None
 1.03A 2aofB-3lr1A:
undetectable		 2aofB-3lr1A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 ALA A  43
THR A   9
PHE A  66
 None
W  A 234 ( 4.0A)
None
 0.77A 2c6nB-3lr1A:
undetectable		 2c6nB-3lr1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 6 TYR A 233
GLY A 170
ASP A 168
ASN A  81
 None
 1.24A 2g72A-3lr1A:
undetectable		 2g72A-3lr1A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 SER A 122
GLY A 123
THR A 124
 W  A 234 ( 4.7A)
None
None
 0.18A 3k9wA-3lr1A:
undetectable		 3k9wA-3lr1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 ARG A 169
VAL A 154
THR A 165
 None
 0.80A 3nduD-3lr1A:
undetectable		 3nduD-3lr1A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 VAL A  54
MET A   6
TYR A 220
ILE A 218
 None
 0.97A 3remA-3lr1A:
undetectable		 3remA-3lr1A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 VAL A  54
MET A   6
TYR A 220
ILE A 218
 None
 0.99A 3remB-3lr1A:
undetectable		 3remB-3lr1A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 PRO A 139
SER A 117
TRP A 132
HIS A 125
 None
 1.20A 4k7gB-3lr1A:
undetectable		 4k7gB-3lr1A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		5 / 12 THR A   9
THR A   8
ALA A  43
ARG A 118
THR A 124
 W  A 234 ( 4.0A)
None
None
W  A 234 ( 3.9A)
None
 1.15A 4qvnV-3lr1A:
undetectable
4qvnb-3lr1A:
undetectable		 4qvnV-3lr1A:
20.37
4qvnb-3lr1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		5 / 12 THR A   9
THR A   8
ALA A  43
ARG A 118
THR A 124
 W  A 234 ( 4.0A)
None
None
W  A 234 ( 3.9A)
None
 1.14A 4qvnH-3lr1A:
undetectable
4qvnN-3lr1A:
undetectable		 4qvnH-3lr1A:
20.37
4qvnN-3lr1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		5 / 12 THR A   9
THR A   8
ALA A  43
ARG A 118
THR A 124
 W  A 234 ( 4.0A)
None
None
W  A 234 ( 3.9A)
None
 1.20A 5lf7V-3lr1A:
undetectable
5lf7b-3lr1A:
undetectable		 5lf7V-3lr1A:
21.54
5lf7b-3lr1A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		5 / 12 THR A   9
THR A   8
ALA A  43
ARG A 118
THR A 124
 W  A 234 ( 4.0A)
None
None
W  A 234 ( 3.9A)
None
 1.17A 6hwdV-3lr1A:
undetectable
6hwdb-3lr1A:
undetectable		 6hwdV-3lr1A:
18.94
6hwdb-3lr1A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3lr1 TUNGSTATE ABC
TRANSPORTER,
PERIPLASMIC
TUNGSTATE-BINDING
PROTEIN
(Geobacter
sulfurreducens) 		5 / 12 THR A   9
THR A   8
ALA A  43
ARG A 118
THR A 124
 W  A 234 ( 4.0A)
None
None
W  A 234 ( 3.9A)
None
 1.17A 6hwdH-3lr1A:
undetectable
6hwdN-3lr1A:
undetectable		 6hwdH-3lr1A:
18.94
6hwdN-3lr1A:
17.12