SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lsg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3lsg TWO-COMPONENT
RESPONSE REGULATOR
YESN
(Fusobacterium
nucleatum) 		4 / 8 MET A 189
ALA A 153
ILE A 157
ASN A 152
 None
 0.92A 1pnlA-3lsgA:
undetectable
1pnlB-3lsgA:
undetectable		 1pnlA-3lsgA:
19.31
1pnlB-3lsgA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3lsg TWO-COMPONENT
RESPONSE REGULATOR
YESN
(Fusobacterium
nucleatum) 		4 / 8 PHE A 240
ASN A 221
GLU A 253
LEU A 214
 None
 1.16A 3rqwC-3lsgA:
undetectable
3rqwD-3lsgA:
undetectable		 3rqwC-3lsgA:
12.42
3rqwD-3lsgA:
12.42