SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		4 / 4 THR B 168
LEU B 167
LEU B 124
GLN B 128
 None
 1.15A 1fbmA-3lsoB:
undetectable		 1fbmA-3lsoB:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 GLU B 299
HIS B 253
LEU B 478
ILE B 301
 None
 0.97A 1tuvA-3lsoB:
undetectable		 1tuvA-3lsoB:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 SER B 345
ALA B 346
SER B 347
ASN B 378
 None
 1.05A 1yvpB-3lsoB:
undetectable		 1yvpB-3lsoB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 ASN B 410
GLY B 452
GLY B 387
ASP B 315
MET B 451
 None
 1.40A 3r24A-3lsoB:
undetectable		 3r24A-3lsoB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.94A 4k8cA-3lsoB:
undetectable		 4k8cA-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.96A 4kahA-3lsoB:
undetectable		 4kahA-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.96A 4kahB-3lsoB:
undetectable		 4kahB-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.94A 4kanA-3lsoB:
undetectable		 4kanA-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.94A 4kanB-3lsoB:
undetectable		 4kanB-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.97A 4kbeA-3lsoB:
undetectable		 4kbeA-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.97A 4kbeB-3lsoB:
undetectable		 4kbeB-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.93A 4lbgA-3lsoB:
undetectable		 4lbgA-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 SER B 381
TYR B 379
PRO B 393
 None
 0.93A 4lbgB-3lsoB:
undetectable		 4lbgB-3lsoB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 GLY B 278
ILE B 272
ILE B 301
LEU B 478
 None
 0.75A 4o8fB-3lsoB:
undetectable		 4o8fB-3lsoB:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 ILE B 140
ALA B  87
LEU B 138
LEU B 164
PHE B  73
 None
 1.34A 4pbhA-3lsoB:
undetectable		 4pbhA-3lsoB:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 GLY B 321
TYR B 319
LEU B 348
ILE B 323
GLY B 452
 None
 1.04A 5d4uC-3lsoB:
undetectable		 5d4uC-3lsoB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3lso PUTATIVE MEMBRANE
ANCHORED PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 TYR B 104
ALA B  57
TYR B 190
 None
 0.86A 5uunB-3lsoB:
undetectable		 5uunB-3lsoB:
22.36