SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3lud PROTEIN ARGONAUTE-2
(Homo
sapiens) 		3 / 3 CYH A 564
PRO A 557
ASP A 480
 None
 0.90A 3hlwB-3ludA:
undetectable		 3hlwB-3ludA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3lud PROTEIN ARGONAUTE-2
(Homo
sapiens) 		3 / 3 CYH A 564
PRO A 557
ASP A 480
 None
 0.90A 4pm5A-3ludA:
undetectable		 4pm5A-3ludA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3lud PROTEIN ARGONAUTE-2
(Homo
sapiens) 		5 / 12 LYS A 509
LEU A 508
MET A 504
ALA A 454
VAL A 519
 None
 1.22A 4x1iB-3ludA:
undetectable		 4x1iB-3ludA:
14.00