SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		4 / 8 LEU A 205
HIS A 208
ASP A 269
LEU A 266
 None
 1.07A 1e7cA-3lulA:
undetectable		 1e7cA-3lulA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		5 / 11 TYR A 114
VAL A  34
ILE A  85
HIS A  45
PHE A 112
 None
 1.39A 1tcoC-3lulA:
undetectable		 1tcoC-3lulA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		5 / 11 TYR A 114
VAL A  34
ILE A  85
HIS A  45
PHE A 112
 None
 1.36A 2dg3A-3lulA:
undetectable		 2dg3A-3lulA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		3 / 3 LEU A 136
PRO A 135
LEU A 139
 None
None
LLP  A 140 ( 4.2A)
 0.56A 2po7B-3lulA:
undetectable		 2po7B-3lulA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		4 / 8 THR A   3
PRO A   2
SER A 105
ALA A  53
 None
 0.96A 2v32A-3lulA:
undetectable
2v32B-3lulA:
undetectable		 2v32A-3lulA:
22.55
2v32B-3lulA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		4 / 8 THR A   3
PRO A   2
SER A 105
ALA A  53
 None
 0.91A 2v32A-3lulA:
undetectable
2v32B-3lulA:
undetectable		 2v32A-3lulA:
22.55
2v32B-3lulA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		4 / 8 THR A   3
PRO A   2
SER A 105
ALA A  53
 None
 0.92A 2v41G-3lulA:
undetectable
2v41H-3lulA:
undetectable		 2v41G-3lulA:
22.55
2v41H-3lulA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		5 / 10 LEU A  49
ILE A  32
LEU A  71
PHE A 109
THR A   3
 None
 1.14A 3fl9E-3lulA:
undetectable		 3fl9E-3lulA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		3 / 3 LEU A 136
PRO A 135
LEU A 139
 None
None
LLP  A 140 ( 4.2A)
 0.55A 3hcrA-3lulA:
undetectable		 3hcrA-3lulA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		3 / 3 ASN A  35
SER A  40
ARG A 204
 None
 0.75A 5b2qA-3lulA:
undetectable		 5b2qA-3lulA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		5 / 12 ILE A  22
PHE A  60
ARG A  48
ILE A  32
LEU A  49
 None
None
LLP  A 140 ( 2.5A)
None
None
 1.27A 5oy02-3lulA:
undetectable		 5oy02-3lulA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Legionella
pneumophila) 		4 / 6 LEU A 262
ASP A 269
GLN A 268
GLN A 211
 None
 1.26A 6g31J-3lulA:
undetectable		 6g31J-3lulA:
16.29