SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3luq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 ALA A 103
VAL A 192
TRP A 182
 None
 0.95A 1c4dA-3luqA:
undetectable
1c4dB-3luqA:
undetectable		 1c4dA-3luqA:
9.78
1c4dB-3luqA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 TRP A 182
ALA A 103
VAL A 192
 None
 0.95A 1c4dA-3luqA:
undetectable
1c4dB-3luqA:
undetectable		 1c4dA-3luqA:
9.78
1c4dB-3luqA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 PHE A 105
TYR A 111
LEU A 124
THR A 196
 None
 1.09A 1o76B-3luqA:
undetectable		 1o76B-3luqA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 PHE A 105
TYR A 111
LEU A 124
ILE A 194
 None
 0.96A 1t87B-3luqA:
undetectable		 1t87B-3luqA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 HIS A 134
HIS A 149
ILE A 141
 None
 0.78A 3u52A-3luqA:
undetectable
3u52C-3luqA:
undetectable		 3u52A-3luqA:
16.19
3u52C-3luqA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3luq SENSOR PROTEIN
(Geobacter
sulfurreducens) 		4 / 4 LEU A 153
ILE A 194
GLY A 191
PHE A 105
 None
 1.05A 4dc3A-3luqA:
undetectable		 4dc3A-3luqA:
15.73