SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VIF_A_FOLA1_0 (DIHYDROFOLATE REDUCTASE)	3lur	PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN (Staphylococcus aureus)	3 / 3	GLN A 124 ILE A 120 TYR A 119	None EDO A 161 (-3.6A) None	0.68A	1vifA-3lurA: undetectable	1vifA-3lurA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBL_A_CAMA517_0 (CYTOCHROME P450-CAM)	3lur	PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN (Staphylococcus aureus)	4 / 7	PHE A 99 TYR A 3 VAL A 155 THR A 127	None	0.98A	2qblA-3lurA: undetectable	2qblA-3lurA: 17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_B_H3PB552_1 (GLUTAMATE DEHYDROGENASE)	3lur	PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN (Staphylococcus aureus)	3 / 3	TYR A 137 TYR A 38 ILE A 43	PG4 A 158 ( 3.8A) PG4 A 158 (-4.6A) None	0.85A	3eteA-3lurA: undetectable 3eteB-3lurA: undetectable	3eteA-3lurA: 15.49 3eteB-3lurA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q5P_A_TACA7101_1 (MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR)	3lur	PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN (Staphylococcus aureus)	5 / 12	VAL A 105 ILE A 73 TYR A 137 TYR A 71 GLU A 135	None None PG4 A 158 ( 3.8A) None None	1.29A	3q5pA-3lurA: 10.2	3q5pA-3lurA: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_D_ACTD403_0 (PROTON-GATED ION CHANNEL)	3lur	PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN (Staphylococcus aureus)	4 / 4	ILE A 30 ARG A 36 TYR A 20 GLU A 18	None EDO A 160 (-4.0A) None None	1.48A	4zzbD-3lurA: undetectable	4zzbD-3lurA: 18.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VIF_A_FOLA1_0","DIHYDROFOLATE REDUCTASE","3lur","PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN","Staphylococcus aureus",3,"GLN A 124;ILE A 120;TYR A 119","None;EDO A 161 (-3.6A);None","0.68A","1vifA-3lurA:undetectable","1vifA-3lurA:18.67"],["2QBL_A_CAMA517_0","CYTOCHROME P450-CAM","3lur","PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN","Staphylococcus aureus",4,"PHE A  99;TYR A   3;VAL A 155;THR A 127","None","0.98A","2qblA-3lurA:undetectable","2qblA-3lurA:17.02"],["3ETE_B_H3PB552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","3lur","PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN","Staphylococcus aureus",3,"TYR A 137;TYR A  38;ILE A  43","PG4 A 158 ( 3.8A);PG4 A 158 (-4.6A);None","0.85A","3eteA-3lurA:undetectable;3eteB-3lurA:undetectable","3eteA-3lurA:15.49;3eteB-3lurA:15.49"],["3Q5P_A_TACA7101_1","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","3lur","PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN","Staphylococcus aureus",5,"VAL A 105;ILE A  73;TYR A 137;TYR A  71;GLU A 135","None;None;PG4 A 158 ( 3.8A);None;None","1.29A","3q5pA-3lurA:10.2","3q5pA-3lurA:18.73"],["4ZZB_D_ACTD403_0","PROTON-GATED ION CHANNEL","3lur","PUTATIVE BACTERIAL TRANSCRIPTION REGULATION PROTEIN","Staphylococcus aureus",4,"ILE A  30;ARG A  36;TYR A  20;GLU A  18","None;EDO A 160 (-4.0A);None;None","1.48A","4zzbD-3lurA:undetectable","4zzbD-3lurA:18.52"]]