SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3luz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 12 GLY A 134
ALA A 135
ILE A 118
VAL A 117
GLY A 116
 None
 0.91A 3ekqA-3luzA:
undetectable		 3ekqA-3luzA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 9 THR A 202
ALA A 198
ALA A 225
GLY A 204
ALA A 246
 None
 1.18A 4qvnK-3luzA:
undetectable
4qvnL-3luzA:
undetectable		 4qvnK-3luzA:
19.86
4qvnL-3luzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 9 THR A 202
ALA A 198
ALA A 225
GLY A 204
ALA A 246
 None
 1.18A 4qvnY-3luzA:
undetectable
4qvnZ-3luzA:
undetectable		 4qvnY-3luzA:
19.86
4qvnZ-3luzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 9 THR A 202
ALA A 198
ALA A 225
GLY A 204
ALA A 246
 None
 1.18A 4qvqK-3luzA:
undetectable
4qvqL-3luzA:
undetectable		 4qvqK-3luzA:
20.59
4qvqL-3luzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 9 THR A 202
ALA A 198
ALA A 225
GLY A 204
ALA A 246
 None
 1.18A 4qvqY-3luzA:
undetectable
4qvqZ-3luzA:
undetectable		 4qvqY-3luzA:
20.59
4qvqZ-3luzA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		4 / 7 GLY A  90
TYR A 170
ASP A 193
TYR A 196
 None
 1.08A 5vlmG-3luzA:
undetectable		 5vlmG-3luzA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		5 / 12 LEU A 192
GLY A 188
THR A  92
ILE A 118
ASP A 214
 None
 1.02A 6emuB-3luzA:
undetectable		 6emuB-3luzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB
(Bartonella
henselae) 		3 / 3 TRP A 206
ILE A 155
GLU A 180
 None
 0.76A 6hcxA-3luzA:
undetectable		 6hcxA-3luzA:
16.67