SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 8 ALA A1568
LEU A1554
LEU A1558
LEU A1583
 None
 0.84A 1ereE-3lvgA:
undetectable		 1ereE-3lvgA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 8 ALA A1568
LEU A1554
LEU A1558
LEU A1583
 None
 0.84A 1ereF-3lvgA:
undetectable		 1ereF-3lvgA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		5 / 12 LEU A1419
LEU A1447
VAL A1448
ALA A1435
PHE A1439
 None
 1.22A 1gseA-3lvgA:
undetectable		 1gseA-3lvgA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		3 / 3 PHE A1557
TRP A1556
GLU A1560
 None
 1.13A 1mogA-3lvgA:
undetectable		 1mogA-3lvgA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 6 LEU A1361
LEU A1336
ILE A1345
GLU A1353
 None
 0.98A 1mt1A-3lvgA:
undetectable
1mt1F-3lvgA:
undetectable		 1mt1A-3lvgA:
8.03
1mt1F-3lvgA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 8 LEU A1361
LEU A1336
ILE A1345
GLU A1353
 None
 0.85A 1n13A-3lvgA:
undetectable
1n13F-3lvgA:
undetectable		 1n13A-3lvgA:
8.03
1n13F-3lvgA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 7 LEU A1361
LEU A1336
ILE A1345
GLU A1353
 None
 0.86A 1n13I-3lvgA:
undetectable
1n13L-3lvgA:
undetectable		 1n13I-3lvgA:
8.03
1n13L-3lvgA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		3 / 3 ALA A1112
VAL A1107
TRP A1108
 None
 0.89A 1nt5A-3lvgA:
undetectable		 1nt5A-3lvgA:
2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		3 / 3 ALA A1112
VAL A1107
TRP A1108
 None
 0.89A 1nt5B-3lvgA:
undetectable		 1nt5B-3lvgA:
2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 5 LEU A1533
ALA A1537
TRP A1556
LEU A1527
 None
 1.03A 2oaxA-3lvgA:
undetectable		 2oaxA-3lvgA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 7 LEU A1361
LEU A1336
ILE A1345
GLU A1353
 None
 1.02A 2qqdA-3lvgA:
undetectable
2qqdE-3lvgA:
undetectable		 2qqdA-3lvgA:
8.59
2qqdE-3lvgA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		5 / 9 ALA A1269
TYR A1290
ILE A1276
GLY A1273
HIS A1279
 None
 1.37A 2zm9A-3lvgA:
0.0		 2zm9A-3lvgA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		5 / 10 GLY A1294
VAL A1261
PHE A1296
PHE A1327
LEU A1323
 None
 0.99A 3a3yA-3lvgA:
undetectable		 3a3yA-3lvgA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3lvg CLATHRIN HEAVY CHAIN
1
(Bos
taurus) 		4 / 5 GLU A1369
THR A1377
HIS A1356
LEU A1349
 None
 1.19A 5axaC-3lvgA:
undetectable		 5axaC-3lvgA:
21.04