SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N3Z_A_ADNA126_1
(RIBONUCLEASE,
SEMINAL)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 9 ALA A  83
ASN A 164
ALA A  73
VAL A  82
HIS A  85
 None
None
None
None
BME  A 191 (-3.7A)
 1.49A 1n3zA-3lvyA:
undetectable		 1n3zA-3lvyA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		3 / 3 VAL A 182
ALA A  83
HIS A  85
 None
None
BME  A 191 (-3.7A)
 0.68A 1q23C-3lvyA:
undetectable		 1q23C-3lvyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		3 / 3 VAL A 182
ALA A  83
HIS A  85
 None
None
BME  A 191 (-3.7A)
 0.69A 1q23H-3lvyA:
undetectable		 1q23H-3lvyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		4 / 6 LEU A 118
THR A 117
PHE A 140
ASP A 152
 None
 1.10A 2wm3A-3lvyA:
undetectable		 2wm3A-3lvyA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 12 SER A  89
ASP A 111
ILE A 109
LEU A 103
ARG A 104
 None
 1.29A 3iv6B-3lvyA:
undetectable		 3iv6B-3lvyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 12 SER A  89
ASP A 111
ILE A 109
LEU A 103
ARG A 104
 None
 1.26A 3iv6D-3lvyA:
undetectable		 3iv6D-3lvyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 12 ASN A  27
VAL A  16
GLY A  36
PHE A  80
ILE A  31
 None
 1.24A 3k13A-3lvyA:
undetectable		 3k13A-3lvyA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 9 VAL A  16
GLY A  36
LEU A  38
THR A  19
VAL A  23
 None
 1.31A 6czmB-3lvyA:
undetectable
6czmC-3lvyA:
undetectable		 6czmB-3lvyA:
21.23
6czmC-3lvyA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 9 VAL A  16
GLY A  36
LEU A  38
THR A  19
VAL A  23
 None
 1.30A 6czmD-3lvyA:
undetectable
6czmE-3lvyA:
undetectable		 6czmD-3lvyA:
21.23
6czmE-3lvyA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3lvy CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
(Streptococcus
mutans) 		5 / 10 VAL A  16
GLY A  36
LEU A  38
THR A  19
VAL A  23
 None
 1.29A 6czmE-3lvyA:
undetectable
6czmF-3lvyA:
undetectable		 6czmE-3lvyA:
21.23
6czmF-3lvyA:
21.23