SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lw0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JLF_A_NVPA999_1 (HIV-1 RT A-CHAIN HIV-1 RT B-CHAIN)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 8	LEU A1091 VAL A1143 CYH A1141 GLY A1085	None	1.03A	1jlfA-3lw0A: undetectable 1jlfB-3lw0A: undetectable	1jlfA-3lw0A: 20.97 1jlfB-3lw0A: 20.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1OPJ_B_STIB4_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 6	LEU A1005 LYS A1033 VAL A1053 MET A1082	None CCX A 1 ( 3.7A) None None	0.88A	1opjB-3lw0A: 31.7	1opjB-3lw0A: 44.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XBB_A_STIA1_1 (TYROSINE-PROTEIN KINASE SYK)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 9	LEU A1005 VAL A1013 ALA A1031 MET A1079 GLY A1085	None None None CCX A 1 ( 3.9A) None	0.41A	1xbbA-3lw0A: 29.3	1xbbA-3lw0A: 33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2HYY_D_STID600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 4	LEU A1005 LYS A1033 VAL A1063 MET A1082	None CCX A 1 ( 3.7A) CCX A 1 (-4.1A) None	0.84A	2hyyD-3lw0A: 32.5	2hyyD-3lw0A: 44.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTH FACTOR RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	GLY A1006 VAL A1013 ALA A1031 MET A1082 GLY A1085 MET A1142 ASP A1153	None None None None None None CCX A 1 ( 4.3A)	1.06A	2wgjA-3lw0A: 32.7	2wgjA-3lw0A: 37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XP2_A_VGHA9000_1 (TYROSINE-PROTEIN KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 9	LEU A1005 VAL A1013 ALA A1031 MET A1082 GLY A1085 GLY A1152	None None None None None CCX A 1 (-3.6A)	0.51A	2xp2A-3lw0A: 30.1	2xp2A-3lw0A: 41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XP2_A_VGHA9000_1 (TYROSINE-PROTEIN KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 9	LEU A1005 VAL A1013 ALA A1031 MET A1082 GLY A1152 ASP A1153	None None None None CCX A 1 (-3.6A) CCX A 1 ( 4.3A)	0.79A	2xp2A-3lw0A: 30.1	2xp2A-3lw0A: 41.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	GLU A1050 ASP A1135 TYR A1165	CCX A 1 ( 4.3A) None None	0.77A	2yvlB-3lw0A: undetectable	2yvlB-3lw0A: 22.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	ARG A1003 LEU A1005 ALA A1031 VAL A1063 LEU A1081 MET A1082 GLY A1085	None None None CCX A 1 (-4.1A) None None None	0.54A	3aoxA-3lw0A: 29.4	3aoxA-3lw0A: 39.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CS9_D_NILD600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 12	ALA A1031 VAL A1053 GLY A1085 PHE A1131 HIS A1133	None None None None CCX A 1 (-4.0A)	0.58A	3cs9D-3lw0A: 31.7	3cs9D-3lw0A: 44.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 7	LYS A1033 VAL A1062 LEU A1081 ILE A1151	CCX A 1 ( 3.7A) None None None	0.94A	3gp0A-3lw0A: 22.8	3gp0A-3lw0A: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 7	VAL A1062 LEU A1081 MET A1082 ILE A1151	None	0.68A	3gp0A-3lw0A: 22.8	3gp0A-3lw0A: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQ7_C_DX2C270_1 (PTERIDINE REDUCTASE 1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 8	PHE A1189 ASP A1135 VAL A1176 LEU A1184	CCX A 1 ( 4.4A) None None None	1.10A	3jq7C-3lw0A: undetectable	3jq7C-3lw0A: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_A_CELA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	VAL A1201 LEU A1202 LEU A1136 ILE A1262 GLY A1117 ALA A1120	None	1.37A	3kk6A-3lw0A: undetectable	3kk6A-3lw0A: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_B_CELB1701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 12	VAL A1201 LEU A1202 LEU A1136 ILE A1262 GLY A1117	None	1.26A	3kk6B-3lw0A: undetectable	3kk6B-3lw0A: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SM2_A_478A126_2 (GAG-PRO-POL POLYPROTEIN)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 11	ALA A1138 VAL A1149 ALA A1116 PRO A1107 LEU A1091	None None None CCX A1287 ( 4.8A) None	1.04A	3sm2B-3lw0A: undetectable	3sm2B-3lw0A: 18.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UE4_A_DB8A601_1 (TYROSINE-PROTEIN KINASE ABL1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	LEU A1005 ALA A1031 LYS A1033 GLU A1050 VAL A1063 MET A1082 GLY A1085	None None CCX A 1 ( 3.7A) CCX A 1 ( 4.3A) CCX A 1 (-4.1A) None None	1.01A	3ue4A-3lw0A: 30.4	3ue4A-3lw0A: 43.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UG2_A_IREA1_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	LEU A1005 VAL A1013 ALA A1031 LYS A1033 LEU A1081 MET A1082 GLY A1085	None None None CCX A 1 ( 3.7A) None None None	0.73A	3ug2A-3lw0A: 28.2	3ug2A-3lw0A: 32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UG2_A_IREA1_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	LEU A1005 VAL A1013 ALA A1031 MET A1079 LEU A1081 MET A1082 GLY A1085	None None None CCX A 1 ( 3.9A) None None None	0.52A	3ug2A-3lw0A: 28.2	3ug2A-3lw0A: 32.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZBF_A_VGHA3000_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	ALA A1031 LEU A1081 MET A1082 GLY A1085 ASP A1086 GLY A1152	None None None None None CCX A 1 (-3.6A)	0.39A	3zbfA-3lw0A: 30.6	3zbfA-3lw0A: 44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZBF_A_VGHA3000_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	LEU A1005 ALA A1031 LEU A1081 MET A1082 GLY A1085 ASP A1086	None	0.40A	3zbfA-3lw0A: 30.6	3zbfA-3lw0A: 44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ANS_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 9	LEU A1005 VAL A1013 ALA A1031 MET A1079 MET A1082 GLY A1085	None None None CCX A 1 ( 3.9A) None None	0.45A	4ansA-3lw0A: 29.9	4ansA-3lw0A: 39.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4CKI_A_ADNA2022_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 11	LEU A1005 GLY A1006 GLY A1008 VAL A1013 ALA A1031 GLY A1085	None	0.62A	4ckiA-3lw0A: 30.3	4ckiA-3lw0A: 39.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 7	ALA A1031 MET A1079 MET A1082 ASP A1086	None CCX A 1 ( 3.9A) None None	0.70A	4l9iA-3lw0A: 8.3	4l9iA-3lw0A: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 7	VAL A1013 ALA A1031 MET A1079 ASP A1086	None None CCX A 1 ( 3.9A) None	0.73A	4l9iA-3lw0A: 8.3	4l9iA-3lw0A: 20.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MKC_A_4MKA1503_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	9 / 12	LEU A1005 GLY A1008 VAL A1013 ALA A1031 LYS A1033 LEU A1081 GLY A1085 ASP A1086 SER A1089	None None None None CCX A 1 ( 3.7A) None None None None	0.70A	4mkcA-3lw0A: 30.4	4mkcA-3lw0A: 37.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4MXX_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	LEU A1005 VAL A1013 ALA A1031 LYS A1033 VAL A1063 MET A1082 GLY A1085	None None None CCX A 1 ( 3.7A) CCX A 1 (-4.1A) None None	0.80A	4mxxB-3lw0A: 29.2	4mxxB-3lw0A: 36.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WBO_C_ANWC601_0 (RHODOPSIN KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 6	ARG A1003 LEU A1005 ALA A1031 MET A1079 MET A1082	None None None CCX A 1 ( 3.9A) None	0.61A	4wboC-3lw0A: 22.4	4wboC-3lw0A: 21.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAA_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 9	LEU A1005 VAL A1013 ALA A1031 MET A1082 GLY A1085 GLY A1152 ASP A1153	None None None None None CCX A 1 (-3.6A) CCX A 1 ( 4.3A)	0.68A	5aaaA-3lw0A: 30.4	5aaaA-3lw0A: 41.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAB_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	LEU A1005 VAL A1013 ALA A1031 LYS A1033 MET A1082 GLY A1085 GLY A1152	None None None CCX A 1 ( 3.7A) None None CCX A 1 (-3.6A)	0.79A	5aabA-3lw0A: 30.2	5aabA-3lw0A: 41.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAB_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	LEU A1005 VAL A1013 ALA A1031 LYS A1033 MET A1082 GLY A1152 ASP A1153	None None None CCX A 1 ( 3.7A) None CCX A 1 (-3.6A) CCX A 1 ( 4.3A)	1.01A	5aabA-3lw0A: 30.2	5aabA-3lw0A: 41.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAC_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	LEU A1005 VAL A1013 ALA A1031 LYS A1033 MET A1082 GLY A1085 GLY A1152	None None None CCX A 1 ( 3.7A) None None CCX A 1 (-3.6A)	0.95A	5aacA-3lw0A: 29.9	5aacA-3lw0A: 41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5AAC_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 10	VAL A1013 ALA A1031 LYS A1033 MET A1082 GLY A1085 GLY A1152 ASP A1153	None None CCX A 1 ( 3.7A) None None CCX A 1 (-3.6A) CCX A 1 ( 4.3A)	1.12A	5aacA-3lw0A: 29.9	5aacA-3lw0A: 41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H2U_A_1N1A501_1 (PROTEIN-TYROSINE KINASE 6)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	ARG A1003 LEU A1005 VAL A1013 ALA A1031 LEU A1081 GLY A1085	None	0.70A	5h2uA-3lw0A: 27.9	5h2uA-3lw0A: 37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H2U_A_1N1A501_1 (PROTEIN-TYROSINE KINASE 6)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	LEU A1005 VAL A1013 ALA A1031 LEU A1081 GLY A1085 GLY A1152	None None None None None CCX A 1 (-3.6A)	0.78A	5h2uA-3lw0A: 27.9	5h2uA-3lw0A: 37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H2U_B_1N1B501_1 (PROTEIN-TYROSINE KINASE 6)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	LEU A1005 VAL A1013 ALA A1031 LEU A1081 GLY A1085 GLY A1152	None None None None None CCX A 1 (-3.6A)	0.79A	5h2uB-3lw0A: 28.2	5h2uB-3lw0A: 37.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 10	GLY A1006 VAL A1013 ALA A1031 MET A1079 LEU A1081 MET A1082	None None None CCX A 1 ( 3.9A) None None	0.73A	5lw1E-3lw0A: 21.5	5lw1E-3lw0A: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_H_ADNH401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 9	GLY A1006 VAL A1013 ALA A1031 MET A1079 LEU A1081 MET A1082	None None None CCX A 1 ( 3.9A) None None	0.69A	5lw1H-3lw0A: 21.7	5lw1H-3lw0A: 13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M35_B_BEZB302_0 (14-3-3 PROTEIN ZETA/DELTA)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	MET A1247 GLN A1250 ARG A1246	None	1.07A	5m35B-3lw0A: 2.9	5m35B-3lw0A: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M36_A_BEZA303_0 (14-3-3 PROTEIN ZETA/DELTA)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	MET A1247 GLN A1250 ARG A1246	None	1.11A	5m36A-3lw0A: undetectable	5m36A-3lw0A: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC3_A_DB8A601_2 (WEE1-LIKE PROTEIN KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 4	VAL A1013 LYS A1033 VAL A1063 ASN A1140	None CCX A 1 ( 3.7A) CCX A 1 (-4.1A) None	0.99A	5vc3A-3lw0A: 22.7	5vc3A-3lw0A: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	6 / 12	LEU A1005 ALA A1031 LYS A1033 VAL A1063 GLY A1085 GLY A1152	None None CCX A 1 ( 3.7A) CCX A 1 (-4.1A) None CCX A 1 (-3.6A)	1.09A	5vcvA-3lw0A: 22.5	5vcvA-3lw0A: 25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 9	LEU A1087 ILE A1205 LEU A1202 PHE A1274 ILE A1263	None	0.89A	5vkqC-3lw0A: undetectable 5vkqD-3lw0A: undetectable	5vkqC-3lw0A: 10.88 5vkqD-3lw0A: 10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W5V_A_ANWA701_0 (SERINE/THREONINE-PRO TEIN KINASE TBK1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	5 / 9	LEU A1005 ALA A1031 VAL A1063 MET A1079 GLY A1085	None None CCX A 1 (-4.1A) CCX A 1 ( 3.9A) None	0.59A	5w5vA-3lw0A: 13.0	5w5vA-3lw0A: 18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	ARG A1003 LEU A1005 VAL A1013 ALA A1031 LYS A1033 LEU A1081 GLY A1085	None None None None CCX A 1 ( 3.7A) None None	0.70A	5y7zA-3lw0A: 22.2	5y7zA-3lw0A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	7 / 12	ARG A1003 LEU A1005 VAL A1013 ALA A1031 LYS A1033 LEU A1081 GLY A1085	None None None None CCX A 1 ( 3.7A) None None	0.70A	5y7zA-3lw0A: 22.2	5y7zA-3lw0A: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CJK_C_ACTC301_0 (IMMUNOGLOBULIN FAB LIGHT CHAIN)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 4	VAL A1063 GLY A1152 ASP A1153 ASP A1086	CCX A 1 (-4.1A) CCX A 1 (-3.6A) CCX A 1 ( 4.3A) None	1.24A	6cjkC-3lw0A: undetectable	6cjkC-3lw0A: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FN9_A_BEZA302_0 (14-3-3 PROTEIN ZETA/DELTA)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	MET A1247 GLN A1250 ARG A1246	None	1.08A	6fn9A-3lw0A: undetectable	6fn9A-3lw0A: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNA_B_BEZB302_0 (14-3-3 PROTEIN ZETA/DELTA)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	MET A1247 GLN A1250 ARG A1246	None	1.04A	6fnaB-3lw0A: 2.2	6fnaB-3lw0A: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNB_A_BEZA301_0 (14-3-3 PROTEIN ZETA/DELTA)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	3 / 3	MET A1247 GLN A1250 ARG A1246	None	1.10A	6fnbA-3lw0A: undetectable	6fnbA-3lw0A: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_1 (TYROSINE-PROTEIN KINASE ABL1)	3lw0	INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR (Homo sapiens)	4 / 6	LEU A1005 VAL A1053 MET A1082 GLY A1085	None	0.52A	6hd4B-3lw0A: 31.4	6hd4B-3lw0A: 23.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JLF_A_NVPA999_1","HIV-1 RT A-CHAIN;HIV-1 RT B-CHAIN","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"LEU A1091;VAL A1143;CYH A1141;GLY A1085","None","1.03A","1jlfA-3lw0A:undetectable;1jlfB-3lw0A:undetectable","1jlfA-3lw0A:20.97;1jlfB-3lw0A:20.73"],["1OPJ_B_STIB4_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"LEU A1005;LYS A1033;VAL A1053;MET A1082","None;CCX A   1 ( 3.7A);None;None","0.88A","1opjB-3lw0A:31.7","1opjB-3lw0A:44.20"],["1XBB_A_STIA1_1","TYROSINE-PROTEIN KINASE SYK","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"LEU A1005;VAL A1013;ALA A1031;MET A1079;GLY A1085","None;None;None;CCX A   1 ( 3.9A);None","0.41A","1xbbA-3lw0A:29.3","1xbbA-3lw0A:33.55"],["2HYY_D_STID600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"LEU A1005;LYS A1033;VAL A1063;MET A1082","None;CCX A   1 ( 3.7A);CCX A   1 (-4.1A);None","0.84A","2hyyD-3lw0A:32.5","2hyyD-3lw0A:44.77"],["2WGJ_A_VGHA2346_1","HEPATOCYTE GROWTH FACTOR RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"GLY A1006;VAL A1013;ALA A1031;MET A1082;GLY A1085;MET A1142;ASP A1153","None;None;None;None;None;None;CCX A   1 ( 4.3A)","1.06A","2wgjA-3lw0A:32.7","2wgjA-3lw0A:37.74"],["2XP2_A_VGHA9000_1","TYROSINE-PROTEIN KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;VAL A1013;ALA A1031;MET A1082;GLY A1085;GLY A1152","None;None;None;None;None;CCX A   1 (-3.6A)","0.51A","2xp2A-3lw0A:30.1","2xp2A-3lw0A:41.35"],["2XP2_A_VGHA9000_1","TYROSINE-PROTEIN KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;VAL A1013;ALA A1031;MET A1082;GLY A1152;ASP A1153","None;None;None;None;CCX A   1 (-3.6A);CCX A   1 ( 4.3A)","0.79A","2xp2A-3lw0A:30.1","2xp2A-3lw0A:41.35"],["2YVL_B_SAMB602_1","HYPOTHETICAL PROTEIN","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"GLU A1050;ASP A1135;TYR A1165","CCX A   1 ( 4.3A);None;None","0.77A","2yvlB-3lw0A:undetectable","2yvlB-3lw0A:22.84"],["3AOX_A_EMHA901_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"ARG A1003;LEU A1005;ALA A1031;VAL A1063;LEU A1081;MET A1082;GLY A1085","None;None;None;CCX A   1 (-4.1A);None;None;None","0.54A","3aoxA-3lw0A:29.4","3aoxA-3lw0A:39.39"],["3CS9_D_NILD600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"ALA A1031;VAL A1053;GLY A1085;PHE A1131;HIS A1133","None;None;None;None;CCX A   1 (-4.0A)","0.58A","3cs9D-3lw0A:31.7","3cs9D-3lw0A:44.81"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"LYS A1033;VAL A1062;LEU A1081;ILE A1151","CCX A   1 ( 3.7A);None;None;None","0.94A","3gp0A-3lw0A:22.8","3gp0A-3lw0A:23.18"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"VAL A1062;LEU A1081;MET A1082;ILE A1151","None","0.68A","3gp0A-3lw0A:22.8","3gp0A-3lw0A:23.18"],["3JQ7_C_DX2C270_1","PTERIDINE REDUCTASE 1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"PHE A1189;ASP A1135;VAL A1176;LEU A1184","CCX A   1 ( 4.4A);None;None;None","1.10A","3jq7C-3lw0A:undetectable","3jq7C-3lw0A:21.16"],["3KK6_A_CELA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"VAL A1201;LEU A1202;LEU A1136;ILE A1262;GLY A1117;ALA A1120","None","1.37A","3kk6A-3lw0A:undetectable","3kk6A-3lw0A:18.53"],["3KK6_B_CELB1701_1","PROSTAGLANDIN G\/H SYNTHASE 1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"VAL A1201;LEU A1202;LEU A1136;ILE A1262;GLY A1117","None","1.26A","3kk6B-3lw0A:undetectable","3kk6B-3lw0A:18.53"],["3SM2_A_478A126_2","GAG-PRO-POL POLYPROTEIN;GAG-PRO-POL POLYPROTEIN","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"ALA A1138;VAL A1149;ALA A1116;PRO A1107;LEU A1091","None;None;None;CCX A1287 ( 4.8A);None","1.04A","3sm2B-3lw0A:undetectable","3sm2B-3lw0A:18.09"],["3UE4_A_DB8A601_1","TYROSINE-PROTEIN KINASE ABL1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;ALA A1031;LYS A1033;GLU A1050;VAL A1063;MET A1082;GLY A1085","None;None;CCX A   1 ( 3.7A);CCX A   1 ( 4.3A);CCX A   1 (-4.1A);None;None","1.01A","3ue4A-3lw0A:30.4","3ue4A-3lw0A:43.53"],["3UG2_A_IREA1_1","EPIDERMAL GROWTH FACTOR RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;LYS A1033;LEU A1081;MET A1082;GLY A1085","None;None;None;CCX A   1 ( 3.7A);None;None;None","0.73A","3ug2A-3lw0A:28.2","3ug2A-3lw0A:32.29"],["3UG2_A_IREA1_1","EPIDERMAL GROWTH FACTOR RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;MET A1079;LEU A1081;MET A1082;GLY A1085","None;None;None;CCX A   1 ( 3.9A);None;None;None","0.52A","3ug2A-3lw0A:28.2","3ug2A-3lw0A:32.29"],["3ZBF_A_VGHA3000_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"ALA A1031;LEU A1081;MET A1082;GLY A1085;ASP A1086;GLY A1152","None;None;None;None;None;CCX A   1 (-3.6A)","0.39A","3zbfA-3lw0A:30.6","3zbfA-3lw0A:44.98"],["3ZBF_A_VGHA3000_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;ALA A1031;LEU A1081;MET A1082;GLY A1085;ASP A1086","None","0.40A","3zbfA-3lw0A:30.6","3zbfA-3lw0A:44.98"],["4ANS_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;VAL A1013;ALA A1031;MET A1079;MET A1082;GLY A1085","None;None;None;CCX A   1 ( 3.9A);None;None","0.45A","4ansA-3lw0A:29.9","4ansA-3lw0A:39.89"],["4CKI_A_ADNA2022_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;GLY A1006;GLY A1008;VAL A1013;ALA A1031;GLY A1085","None","0.62A","4ckiA-3lw0A:30.3","4ckiA-3lw0A:39.05"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"ALA A1031;MET A1079;MET A1082;ASP A1086","None;CCX A   1 ( 3.9A);None;None","0.70A","4l9iA-3lw0A:8.3","4l9iA-3lw0A:20.74"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"VAL A1013;ALA A1031;MET A1079;ASP A1086","None;None;CCX A   1 ( 3.9A);None","0.73A","4l9iA-3lw0A:8.3","4l9iA-3lw0A:20.74"],["4MKC_A_4MKA1503_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",9,"LEU A1005;GLY A1008;VAL A1013;ALA A1031;LYS A1033;LEU A1081;GLY A1085;ASP A1086;SER A1089","None;None;None;None;CCX A   1 ( 3.7A);None;None;None;None","0.70A","4mkcA-3lw0A:30.4","4mkcA-3lw0A:37.33"],["4MXX_B_DB8B601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;LYS A1033;VAL A1063;MET A1082;GLY A1085","None;None;None;CCX A   1 ( 3.7A);CCX A   1 (-4.1A);None;None","0.80A","4mxxB-3lw0A:29.2","4mxxB-3lw0A:36.62"],["4WBO_C_ANWC601_0","RHODOPSIN KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"ARG A1003;LEU A1005;ALA A1031;MET A1079;MET A1082","None;None;None;CCX A   1 ( 3.9A);None","0.61A","4wboC-3lw0A:22.4","4wboC-3lw0A:21.44"],["5AAA_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;MET A1082;GLY A1085;GLY A1152;ASP A1153","None;None;None;None;None;CCX A   1 (-3.6A);CCX A   1 ( 4.3A)","0.68A","5aaaA-3lw0A:30.4","5aaaA-3lw0A:41.06"],["5AAB_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;LYS A1033;MET A1082;GLY A1085;GLY A1152","None;None;None;CCX A   1 ( 3.7A);None;None;CCX A   1 (-3.6A)","0.79A","5aabA-3lw0A:30.2","5aabA-3lw0A:41.06"],["5AAB_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;LYS A1033;MET A1082;GLY A1152;ASP A1153","None;None;None;CCX A   1 ( 3.7A);None;CCX A   1 (-3.6A);CCX A   1 ( 4.3A)","1.01A","5aabA-3lw0A:30.2","5aabA-3lw0A:41.06"],["5AAC_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"LEU A1005;VAL A1013;ALA A1031;LYS A1033;MET A1082;GLY A1085;GLY A1152","None;None;None;CCX A   1 ( 3.7A);None;None;CCX A   1 (-3.6A)","0.95A","5aacA-3lw0A:29.9","5aacA-3lw0A:41.35"],["5AAC_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"VAL A1013;ALA A1031;LYS A1033;MET A1082;GLY A1085;GLY A1152;ASP A1153","None;None;CCX A   1 ( 3.7A);None;None;CCX A   1 (-3.6A);CCX A   1 ( 4.3A)","1.12A","5aacA-3lw0A:29.9","5aacA-3lw0A:41.35"],["5H2U_A_1N1A501_1","PROTEIN-TYROSINE KINASE 6","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"ARG A1003;LEU A1005;VAL A1013;ALA A1031;LEU A1081;GLY A1085","None","0.70A","5h2uA-3lw0A:27.9","5h2uA-3lw0A:37.05"],["5H2U_A_1N1A501_1","PROTEIN-TYROSINE KINASE 6","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;VAL A1013;ALA A1031;LEU A1081;GLY A1085;GLY A1152","None;None;None;None;None;CCX A   1 (-3.6A)","0.78A","5h2uA-3lw0A:27.9","5h2uA-3lw0A:37.05"],["5H2U_B_1N1B501_1","PROTEIN-TYROSINE KINASE 6","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;VAL A1013;ALA A1031;LEU A1081;GLY A1085;GLY A1152","None;None;None;None;None;CCX A   1 (-3.6A)","0.79A","5h2uB-3lw0A:28.2","5h2uB-3lw0A:37.05"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"GLY A1006;VAL A1013;ALA A1031;MET A1079;LEU A1081;MET A1082","None;None;None;CCX A   1 ( 3.9A);None;None","0.73A","5lw1E-3lw0A:21.5","5lw1E-3lw0A:13.29"],["5LW1_H_ADNH401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"GLY A1006;VAL A1013;ALA A1031;MET A1079;LEU A1081;MET A1082","None;None;None;CCX A   1 ( 3.9A);None;None","0.69A","5lw1H-3lw0A:21.7","5lw1H-3lw0A:13.29"],["5M35_B_BEZB302_0","14-3-3 PROTEIN ZETA\/DELTA","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"MET A1247;GLN A1250;ARG A1246","None","1.07A","5m35B-3lw0A:2.9","5m35B-3lw0A:21.84"],["5M36_A_BEZA303_0","14-3-3 PROTEIN ZETA\/DELTA","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"MET A1247;GLN A1250;ARG A1246","None","1.11A","5m36A-3lw0A:undetectable","5m36A-3lw0A:21.84"],["5VC3_A_DB8A601_2","WEE1-LIKE PROTEIN KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"VAL A1013;LYS A1033;VAL A1063;ASN A1140","None;CCX A   1 ( 3.7A);CCX A   1 (-4.1A);None","0.99A","5vc3A-3lw0A:22.7","5vc3A-3lw0A:23.24"],["5VCV_A_1N1A404_1","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",6,"LEU A1005;ALA A1031;LYS A1033;VAL A1063;GLY A1085;GLY A1152","None;None;CCX A   1 ( 3.7A);CCX A   1 (-4.1A);None;CCX A   1 (-3.6A)","1.09A","5vcvA-3lw0A:22.5","5vcvA-3lw0A:25.14"],["5VKQ_C_PCFC1805_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"LEU A1087;ILE A1205;LEU A1202;PHE A1274;ILE A1263","None","0.89A","5vkqC-3lw0A:undetectable;5vkqD-3lw0A:undetectable","5vkqC-3lw0A:10.88;5vkqD-3lw0A:10.88"],["5W5V_A_ANWA701_0","SERINE\/THREONINE-PROTEIN KINASE TBK1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",5,"LEU A1005;ALA A1031;VAL A1063;MET A1079;GLY A1085","None;None;CCX A   1 (-4.1A);CCX A   1 ( 3.9A);None","0.59A","5w5vA-3lw0A:13.0","5w5vA-3lw0A:18.71"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"ARG A1003;LEU A1005;VAL A1013;ALA A1031;LYS A1033;LEU A1081;GLY A1085","None;None;None;None;CCX A   1 ( 3.7A);None;None","0.70A","5y7zA-3lw0A:22.2","5y7zA-3lw0A:14.77"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",7,"ARG A1003;LEU A1005;VAL A1013;ALA A1031;LYS A1033;LEU A1081;GLY A1085","None;None;None;None;CCX A   1 ( 3.7A);None;None","0.70A","5y7zA-3lw0A:22.2","5y7zA-3lw0A:21.60"],["6CJK_C_ACTC301_0","IMMUNOGLOBULIN FAB LIGHT CHAIN","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"VAL A1063;GLY A1152;ASP A1153;ASP A1086","CCX A   1 (-4.1A);CCX A   1 (-3.6A);CCX A   1 ( 4.3A);None","1.24A","6cjkC-3lw0A:undetectable","6cjkC-3lw0A:21.60"],["6FN9_A_BEZA302_0","14-3-3 PROTEIN ZETA\/DELTA","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"MET A1247;GLN A1250;ARG A1246","None","1.08A","6fn9A-3lw0A:undetectable","6fn9A-3lw0A:21.69"],["6FNA_B_BEZB302_0","14-3-3 PROTEIN ZETA\/DELTA","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"MET A1247;GLN A1250;ARG A1246","None","1.04A","6fnaB-3lw0A:2.2","6fnaB-3lw0A:21.69"],["6FNB_A_BEZA301_0","14-3-3 PROTEIN ZETA\/DELTA","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",3,"MET A1247;GLN A1250;ARG A1246","None","1.10A","6fnbA-3lw0A:undetectable","6fnbA-3lw0A:21.69"],["6HD4_B_STIB602_1","TYROSINE-PROTEIN KINASE ABL1","3lw0","INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR","Homo sapiens",4,"LEU A1005;VAL A1053;MET A1082;GLY A1085","None","0.52A","6hd4B-3lw0A:31.4","6hd4B-3lw0A:23.08"]]