SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lwd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 1jffB-3lwdA:
undetectable		 1jffB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A 195
ILE A 188
TRP A 223
 None
 1.15A 1nodB-3lwdA:
undetectable		 1nodB-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A   9
ILE A 188
TRP A 223
 None
 0.90A 1qomA-3lwdA:
undetectable		 1qomA-3lwdA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 6 SER A 174
ALA A 175
SER A 176
THR A 154
 None
 1.04A 1yvpB-3lwdA:
undetectable		 1yvpB-3lwdA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 2hxfB-3lwdA:
undetectable		 2hxfB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 2hxhB-3lwdA:
undetectable		 2hxhB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 7 SER A 174
ALA A 175
SER A 176
THR A 154
 None
 1.02A 2i91A-3lwdA:
undetectable		 2i91A-3lwdA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 7 SER A 174
ALA A 175
SER A 176
THR A 154
 None
 1.03A 2i91B-3lwdA:
undetectable		 2i91B-3lwdA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A   9
ILE A 188
TRP A 223
 None
 0.90A 2nodB-3lwdA:
undetectable		 2nodB-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A 195
ILE A 188
TRP A 223
 None
 1.12A 2nodB-3lwdA:
undetectable		 2nodB-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 2p4nB-3lwdA:
undetectable		 2p4nB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 PHE A  97
SER A  78
LEU A  82
 None
 0.83A 2w1bA-3lwdA:
undetectable		 2w1bA-3lwdA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 2wbeB-3lwdA:
undetectable		 2wbeB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 3dcoB-3lwdA:
undetectable		 3dcoB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.80A 3edlB-3lwdA:
undetectable		 3edlB-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 LEU A 100
LEU A 173
THR A 172
ARG A  69
GLY A 131
 None
 0.76A 3iz0B-3lwdA:
undetectable		 3iz0B-3lwdA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A   9
ILE A 188
TRP A 223
 None
 1.03A 3nw2A-3lwdA:
undetectable		 3nw2A-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A 195
ILE A 188
TRP A 223
 None
 1.08A 3nw2A-3lwdA:
undetectable		 3nw2A-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A   9
ILE A 188
TRP A 223
 None
 0.92A 3nw2B-3lwdA:
undetectable		 3nw2B-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		3 / 3 ARG A 195
ILE A 188
TRP A 223
 None
 1.10A 3nw2B-3lwdA:
undetectable		 3nw2B-3lwdA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 7 LEU A 215
ILE A 188
THR A 138
GLY A 136
 None
 0.89A 4eq4A-3lwdA:
undetectable		 4eq4A-3lwdA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 7 LEU A 215
ILE A 188
THR A 138
GLY A 136
 None
 0.85A 4eqlB-3lwdA:
undetectable		 4eqlB-3lwdA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 7 TRP A  58
GLU A  94
ARG A  84
VAL A  61
 None
 1.48A 4jseA-3lwdA:
undetectable
4jseB-3lwdA:
undetectable		 4jseA-3lwdA:
20.65
4jseB-3lwdA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		4 / 6 LEU A 215
ILE A 188
THR A 138
GLY A 136
 None
 0.78A 4l39A-3lwdA:
undetectable		 4l39A-3lwdA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3lwd 6-PHOSPHOGLUCONOLACT
ONASE
(Chromohalobacter
salexigens) 		5 / 12 THR A 138
GLY A  40
GLY A 131
LEU A 130
ALA A  80
 None
 1.01A 5c0oG-3lwdA:
3.2		 5c0oG-3lwdA:
25.00