SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3lwz 3-DEHYDROQUINATE
DEHYDRATASE
(Yersinia
pestis) 		4 / 7 ALA A 142
ILE A 100
ILE A 127
PHE A 137
 None
 0.89A 1upfB-3lwzA:
3.2		 1upfB-3lwzA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 3lwz 3-DEHYDROQUINATE
DEHYDRATASE
(Yersinia
pestis) 		6 / 12 ALA A 132
ASP A 133
ILE A 102
ILE A 127
GLY A 129
LEU A  15
 None
 1.32A 2o4nA-3lwzA:
undetectable		 2o4nA-3lwzA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)		 3lwz 3-DEHYDROQUINATE
DEHYDRATASE
(Yersinia
pestis) 		5 / 12 VAL A  35
ILE A 102
LEU A 119
LEU A  15
ALA A  80
 None
 1.23A 5fctB-3lwzA:
undetectable		 5fctB-3lwzA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3lwz 3-DEHYDROQUINATE
DEHYDRATASE
(Yersinia
pestis) 		5 / 12 ILE A  61
VAL A  47
VAL A  95
ALA A  91
LEU A  49
 None
 0.87A 6a7pB-3lwzA:
undetectable		 6a7pB-3lwzA:
12.14