SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lx6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
THR A 244
 None
 1.19A 1ddsA-3lx6A:
undetectable		 1ddsA-3lx6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 6 PHE A  87
GLU A 451
LEU A 450
MET A 220
 None
 1.05A 1hk1A-3lx6A:
undetectable		 1hk1A-3lx6A:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 8 PHE A  93
GLU A 115
ASP A 140
ILE A 141
PRO A 176
LEU A 205
 None
 0.67A 1hmyA-3lx6A:
30.3		 1hmyA-3lx6A:
33.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		3 / 3 ASP A 293
ASP A 298
LYS A 453
 None
 0.77A 1lqtB-3lx6A:
3.4		 1lqtB-3lx6A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		3 / 3 ASP A 293
ASP A 298
LYS A 453
 None
 0.74A 1lquB-3lx6A:
3.1		 1lquB-3lx6A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 1.02A 1rd7B-3lx6A:
undetectable		 1rd7B-3lx6A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 1.00A 1re7A-3lx6A:
undetectable		 1re7A-3lx6A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 LEU A 172
PHE A 137
HIS A 128
ARG A 101
PHE A  89
 None
 1.30A 1skxA-3lx6A:
undetectable		 1skxA-3lx6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.26A 2d0kB-3lx6A:
undetectable		 2d0kB-3lx6A:
18.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 PHE A  93
GLY A  95
GLY A  97
ILE A 141
PRO A 176
LEU A 205
 None
 1.05A 2hmyB-3lx6A:
30.5		 2hmyB-3lx6A:
33.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		8 / 12 PHE A  93
GLY A  95
GLY A  98
ASP A 140
ILE A 141
PRO A 176
LEU A 205
VAL A 438
 None
 0.59A 2hmyB-3lx6A:
30.5		 2hmyB-3lx6A:
33.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		3 / 3 ASP A 377
ARG A 400
ARG A 378
 None
 1.11A 2j9dA-3lx6A:
undetectable
2j9dC-3lx6A:
undetectable		 2j9dA-3lx6A:
14.63
2j9dC-3lx6A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 6 PRO A 218
MET A 220
ASP A 251
TYR A 250
 None
 1.42A 2lh8A-3lx6A:
undetectable		 2lh8A-3lx6A:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		3 / 3 ARG A 405
ASN A 436
THR A 123
 None
 0.82A 2q63A-3lx6A:
undetectable		 2q63A-3lx6A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 240
LEU A 281
PHE A 175
GLN A 178
THR A 244
 None
 1.21A 2w3mB-3lx6A:
undetectable		 2w3mB-3lx6A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		7 / 12 PHE A  93
GLY A  95
GLY A  98
PRO A 176
LEU A 205
ASN A 436
VAL A 438
 None
 0.97A 3av6A-3lx6A:
3.9		 3av6A-3lx6A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 PHE A  93
GLY A  97
PRO A 176
LEU A 205
ASN A 436
 None
 1.10A 3av6A-3lx6A:
3.9		 3av6A-3lx6A:
14.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 PHE A  93
GLY A  97
ILE A 141
PRO A 176
LEU A 205
 None
 1.01A 3eeoA-3lx6A:
24.8		 3eeoA-3lx6A:
33.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 PHE A  93
GLY A  98
ASP A 140
ILE A 141
PRO A 176
LEU A 205
 None
 0.79A 3eeoA-3lx6A:
24.8		 3eeoA-3lx6A:
33.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		3 / 3 GLU A 115
SER A 437
VAL A 438
 None
 0.74A 3eeoA-3lx6A:
29.3		 3eeoA-3lx6A:
33.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 5 GLY A  97
ILE A  96
VAL A 440
SER A 437
 None
 1.20A 4d33B-3lx6A:
undetectable		 4d33B-3lx6A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 5 PHE A 434
PHE A 421
ILE A  96
GLY A  97
 None
 0.96A 4ejjC-3lx6A:
undetectable		 4ejjC-3lx6A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 6 GLY A 107
GLY A 108
GLU A 451
ILE A 454
 None
 0.94A 4fglD-3lx6A:
3.8		 4fglD-3lx6A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.23A 4fhbA-3lx6A:
undetectable		 4fhbA-3lx6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.25A 4kjlA-3lx6A:
undetectable		 4kjlA-3lx6A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.20A 4pthA-3lx6A:
undetectable		 4pthA-3lx6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 1.05A 4ptjA-3lx6A:
undetectable		 4ptjA-3lx6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 8 PHE A 103
SER A 105
LEU A 450
PHE A 238
 None
 0.99A 4rkuA-3lx6A:
undetectable
4rkuJ-3lx6A:
undetectable		 4rkuA-3lx6A:
19.34
4rkuJ-3lx6A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.19A 4x5gB-3lx6A:
undetectable		 4x5gB-3lx6A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.10A 4x5iA-3lx6A:
undetectable		 4x5iA-3lx6A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 0.96A 4x5jA-3lx6A:
undetectable		 4x5jA-3lx6A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 0.97A 5e8qA-3lx6A:
undetectable		 5e8qA-3lx6A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.17A 5eajA-3lx6A:
undetectable		 5eajA-3lx6A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 GLY A 249
LEU A 281
ILE A 265
PHE A 238
MET A 242
 None
 1.17A 5eskA-3lx6A:
undetectable		 5eskA-3lx6A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 11 PHE A  93
GLY A  95
GLU A 115
ASN A 117
ASP A 140
 None
 0.53A 5hjiA-3lx6A:
7.0		 5hjiA-3lx6A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 7 PHE A  89
ASP A  91
GLY A 102
GLY A  98
 None
 0.97A 5n9xA-3lx6A:
undetectable		 5n9xA-3lx6A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.18A 5ujxA-3lx6A:
undetectable		 5ujxA-3lx6A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.22A 5z6jA-3lx6A:
undetectable		 5z6jA-3lx6A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		6 / 12 ILE A 213
THR A 145
ILE A 141
LEU A  92
ILE A 212
THR A 244
 None
 1.22A 5z6kA-3lx6A:
undetectable		 5z6kA-3lx6A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 10 PHE A 103
SER A 105
GLY A 107
ILE A 106
PHE A  87
 None
 1.24A 6ebpB-3lx6A:
undetectable		 6ebpB-3lx6A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 10 PHE A 103
SER A 105
GLY A 107
ILE A 106
PHE A  87
 None
 1.25A 6ebpC-3lx6A:
undetectable		 6ebpC-3lx6A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		4 / 5 ARG A 122
ALA A 126
GLN A 433
ILE A  96
 None
 1.21A 6g9bA-3lx6A:
undetectable
6g9bB-3lx6A:
undetectable		 6g9bA-3lx6A:
15.06
6g9bB-3lx6A:
13.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		8 / 12 PHE A  93
GLY A  95
GLY A  98
ASP A 140
ILE A 141
ASN A 436
SER A 437
VAL A 438
 None
 0.65A 6mhtA-3lx6A:
27.7		 6mhtA-3lx6A:
33.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 PHE A  93
GLY A  97
ILE A 141
ASN A 436
SER A 437
 None
 0.98A 6mhtA-3lx6A:
27.7		 6mhtA-3lx6A:
33.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE
(Shigella
flexneri) 		5 / 12 ILE A 213
THR A 145
ILE A 141
ILE A 212
THR A 244
 None
 1.00A 7dfrA-3lx6A:
undetectable		 7dfrA-3lx6A:
17.41