SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3lxf FERREDOXIN
(Novosphingobium
aromaticivorans) 		6 / 12 VAL A  99
ILE A   4
ILE A  16
ILE A  33
VAL A  51
LEU A  36
 None
 1.17A 1qhsA-3lxfA:
undetectable		 1qhsA-3lxfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3lxf FERREDOXIN
(Novosphingobium
aromaticivorans) 		6 / 12 VAL A  99
ILE A   4
ILE A  16
ILE A  33
VAL A  51
LEU A  36
 None
 1.21A 1qhyA-3lxfA:
undetectable		 1qhyA-3lxfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3lxf FERREDOXIN
(Novosphingobium
aromaticivorans) 		4 / 6 CYH A  49
THR A  48
CYH A  86
GLY A  42
 FES  A 500 (-2.3A)
None
FES  A 500 (-2.3A)
FES  A 500 (-3.6A)
 1.39A 3w9tE-3lxfA:
undetectable		 3w9tE-3lxfA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3lxf FERREDOXIN
(Novosphingobium
aromaticivorans) 		4 / 4 ASP A  30
ILE A  90
PRO A  20
LEU A  22
 None
 1.43A 6mkeB-3lxfA:
undetectable		 6mkeB-3lxfA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3lxf FERREDOXIN
(Novosphingobium
aromaticivorans) 		4 / 4 ASP A  30
ILE A  90
PRO A  20
LEU A  22
 None
 1.38A 6mkeA-3lxfA:
undetectable		 6mkeA-3lxfA:
20.19