SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lxt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 160
LEU A 150
LEU A 145
VAL A 186
ALA A 166
 GOL  A3969 (-3.4A)
GOL  A3969 (-3.7A)
CL  A 528 (-3.9A)
None
None
 1.19A 1gseA-3lxtA:
13.9		 1gseA-3lxtA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		4 / 7 LEU A  94
VAL A  97
GLY A  98
ILE A  69
 None
 0.77A 1p2yA-3lxtA:
undetectable		 1p2yA-3lxtA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		4 / 7 PHE A  42
ILE A  69
ILE A 161
GLY A   7
 None
 0.99A 2v0mB-3lxtA:
undetectable		 2v0mB-3lxtA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		4 / 8 GLN A 135
ASP A 176
TYR A 138
TRP A 167
 None
 1.39A 2xz5A-3lxtA:
undetectable
2xz5C-3lxtA:
undetectable		 2xz5A-3lxtA:
20.00
2xz5C-3lxtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		3 / 3 GLN A 171
PHE A 178
TYR A 138
 None
 0.98A 3ucjB-3lxtA:
undetectable		 3ucjB-3lxtA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3lxt GLUTATHIONE S
TRANSFERASE
(Pseudomonas
protegens) 		3 / 3 GLN A 171
PHE A 178
TYR A 138
 None
 0.96A 3ucjA-3lxtA:
undetectable		 3ucjA-3lxtA:
23.72