SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		5 / 12 LEU A 164
ASP A 163
LEU A 178
GLY A 169
PHE A 112
 None
 1.45A 1d4fA-3lxzA:
undetectable		 1d4fA-3lxzA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		5 / 11 VAL A  89
ALA A 154
LEU A  93
LEU A  78
ASP A  67
 None
 1.34A 2c12F-3lxzA:
undetectable		 2c12F-3lxzA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 8 PHE A 133
PHE A 181
GLY A 169
PHE A 142
 None
 1.01A 3ko0B-3lxzA:
undetectable
3ko0J-3lxzA:
undetectable		 3ko0B-3lxzA:
19.65
3ko0J-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 8 GLY A 169
PHE A 142
PHE A 133
PHE A 181
 None
 0.93A 3ko0K-3lxzA:
undetectable
3ko0S-3lxzA:
undetectable		 3ko0K-3lxzA:
19.65
3ko0S-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 7 GLY A 169
PHE A 142
PHE A 133
PHE A 181
 None
 1.03A 3ko0L-3lxzA:
undetectable
3ko0N-3lxzA:
undetectable		 3ko0L-3lxzA:
19.65
3ko0N-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 8 GLY A 169
PHE A 142
PHE A 133
PHE A 181
 None
 0.98A 3ko0O-3lxzA:
undetectable
3ko0Q-3lxzA:
undetectable		 3ko0O-3lxzA:
19.65
3ko0Q-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 7 PHE A 133
PHE A 181
GLY A 169
PHE A 142
 None
 1.00A 3ko0K-3lxzA:
undetectable
3ko0S-3lxzA:
undetectable		 3ko0K-3lxzA:
19.65
3ko0S-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 7 PHE A 133
PHE A 181
GLY A 169
PHE A 142
 None
 1.04A 3ko0R-3lxzA:
undetectable
3ko0T-3lxzA:
undetectable		 3ko0R-3lxzA:
19.65
3ko0T-3lxzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 6 LEU A  25
LEU A  20
LEU A 153
LEU A  66
 None
 0.98A 3q1eA-3lxzA:
undetectable
3q1eC-3lxzA:
undetectable		 3q1eA-3lxzA:
17.78
3q1eC-3lxzA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3lxz GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN
(Pseudomonas
putida) 		4 / 6 LEU A 153
LEU A  66
LEU A  25
LEU A  20
 None
 1.02A 3q1eA-3lxzA:
undetectable
3q1eC-3lxzA:
undetectable		 3q1eA-3lxzA:
17.78
3q1eC-3lxzA:
17.78