SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3lyb PUTATIVE
ENDORIBONUCLEASE
(Klebsiella
pneumoniae) 		3 / 3 GLN A  99
LYS A  96
VAL A  94
 None
 0.92A 2jfaB-3lybA:
undetectable		 2jfaB-3lybA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3lyb PUTATIVE
ENDORIBONUCLEASE
(Klebsiella
pneumoniae) 		3 / 3 VAL A 147
VAL A  94
GLN A  90
 None
 0.72A 5qgwA-3lybA:
undetectable		 5qgwA-3lybA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3lyb PUTATIVE
ENDORIBONUCLEASE
(Klebsiella
pneumoniae) 		4 / 9 ILE A  80
ILE A 141
ILE A  69
LEU A  70
 None
 0.75A 5vkqB-3lybA:
undetectable
5vkqC-3lybA:
undetectable		 5vkqB-3lybA:
7.16
5vkqC-3lybA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3lyb PUTATIVE
ENDORIBONUCLEASE
(Klebsiella
pneumoniae) 		4 / 8 ILE A  29
GLN A  99
TYR A 110
VAL A  94
 None
 1.08A 5vlmF-3lybA:
undetectable		 5vlmF-3lybA:
21.72