SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lyc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 158
PHE A 147
ILE A 126
PHE A 135
 None
 1.02A 2q6hA-3lycA:
undetectable		 2q6hA-3lycA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 158
PHE A 147
ILE A 126
PHE A 135
 None
 1.02A 2qb4A-3lycA:
undetectable		 2qb4A-3lycA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		5 / 12 GLY A 201
GLY A 221
SER A 222
GLY A 223
ASP A 224
 None
 0.95A 3huoB-3lycA:
undetectable		 3huoB-3lycA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		6 / 12 GLY A 201
THR A 185
GLY A 221
SER A 222
GLY A 223
ASP A 224
 None
 1.08A 3q07B-3lycA:
undetectable		 3q07B-3lycA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		5 / 9 VAL A  53
VAL A  52
ILE A  87
GLY A  48
ALA A 118
 None
 1.24A 4fwdA-3lycA:
undetectable		 4fwdA-3lycA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		4 / 6 ASN A 177
GLU A 175
GLU A 196
GLU A 216
 None
 1.36A 4r87H-3lycA:
undetectable		 4r87H-3lycA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3lyc PUTATIVE PECTINASE
(Parabacteroides
distasonis) 		5 / 12 GLY A 221
GLY A 203
SER A 202
ARG A 206
GLY A 260
 None
 1.14A 5hikA-3lycA:
undetectable		 5hikA-3lycA:
21.71