SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3lyd UNCHARACTERIZED
PROTEIN
(Jonesia
denitrificans) 		4 / 6 GLU A 117
ILE A 126
ALA A  57
ASN A  64
 None
 1.06A 3pgyA-3lydA:
undetectable
3pgyB-3lydA:
undetectable		 3pgyA-3lydA:
18.12
3pgyB-3lydA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3lyd UNCHARACTERIZED
PROTEIN
(Jonesia
denitrificans) 		3 / 3 GLU A 117
GLY A  60
SER A 119
 None
 0.69A 4b53B-3lydA:
undetectable		 4b53B-3lydA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3lyd UNCHARACTERIZED
PROTEIN
(Jonesia
denitrificans) 		3 / 3 TYR A   6
HIS A 120
ARG A  56
 None
 1.01A 4htfA-3lydA:
undetectable		 4htfA-3lydA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3lyd UNCHARACTERIZED
PROTEIN
(Jonesia
denitrificans) 		3 / 3 ARG A  84
TYR A  79
GLU A  81
 None
 0.48A 4zzbE-3lydA:
undetectable		 4zzbE-3lydA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3lyd UNCHARACTERIZED
PROTEIN
(Jonesia
denitrificans) 		4 / 6 GLY A  16
THR A  15
VAL A 154
HIS A 157
 None
 1.05A 5ewuA-3lydA:
undetectable		 5ewuA-3lydA:
17.62