SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FML_A_RTLA401_0 (RETINOL DEHYDRATASE)	3lys	PROPHAGE PI2 PROTEIN 01, INTEGRASE (Lactococcus lactis)	5 / 12	TYR A 63 LEU A 138 SER A 134 TYR A 108 ILE A 103	None	1.00A	1fmlA-3lysA: undetectable	1fmlA-3lysA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FML_A_RTLA401_0 (RETINOL DEHYDRATASE)	3lys	PROPHAGE PI2 PROTEIN 01, INTEGRASE (Lactococcus lactis)	5 / 12	TYR A 63 LEU A 138 SER A 134 TYR A 108 PHE A 115	None	1.28A	1fmlA-3lysA: undetectable	1fmlA-3lysA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FML_B_RTLB501_0 (RETINOL DEHYDRATASE)	3lys	PROPHAGE PI2 PROTEIN 01, INTEGRASE (Lactococcus lactis)	5 / 12	TYR A 63 LEU A 138 SER A 134 TYR A 108 ILE A 103	None	1.00A	1fmlB-3lysA: undetectable	1fmlB-3lysA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO5_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	3lys	PROPHAGE PI2 PROTEIN 01, INTEGRASE (Lactococcus lactis)	5 / 9	LEU A 112 VAL A 154 ALA A 152 LEU A 91 MET A 95	None	1.47A	2qo5A-3lysA: undetectable	2qo5A-3lysA: 23.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FML_A_RTLA401_0","RETINOL DEHYDRATASE","3lys","PROPHAGE PI2 PROTEIN 01, INTEGRASE","Lactococcus lactis",5,"TYR A  63;LEU A 138;SER A 134;TYR A 108;ILE A 103","None","1.00A","1fmlA-3lysA:undetectable","1fmlA-3lysA:14.81"],["1FML_A_RTLA401_0","RETINOL DEHYDRATASE","3lys","PROPHAGE PI2 PROTEIN 01, INTEGRASE","Lactococcus lactis",5,"TYR A  63;LEU A 138;SER A 134;TYR A 108;PHE A 115","None","1.28A","1fmlA-3lysA:undetectable","1fmlA-3lysA:14.81"],["1FML_B_RTLB501_0","RETINOL DEHYDRATASE","3lys","PROPHAGE PI2 PROTEIN 01, INTEGRASE","Lactococcus lactis",5,"TYR A  63;LEU A 138;SER A 134;TYR A 108;ILE A 103","None","1.00A","1fmlB-3lysA:undetectable","1fmlB-3lysA:14.81"],["2QO5_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","3lys","PROPHAGE PI2 PROTEIN 01, INTEGRASE","Lactococcus lactis",5,"LEU A 112;VAL A 154;ALA A 152;LEU A  91;MET A  95","None","1.47A","2qo5A-3lysA:undetectable","2qo5A-3lysA:23.70"]]