SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lyu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_A_ADNA1001_1
(CLASS B ACID
PHOSPHATASE)		 3lyu PUTATIVE HYDROGENASE
(Pyrococcus
furiosus) 		5 / 10 LYS A 101
GLU A 187
LEU A 103
GLY A 106
THR A 150
 None
 1.24A 2b82A-3lyuA:
3.8		 2b82A-3lyuA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 3lyu PUTATIVE HYDROGENASE
(Pyrococcus
furiosus) 		5 / 9 LEU A 176
GLY A 106
VAL A 204
VAL A 180
LEU A 184
 None
 1.11A 4qd3A-3lyuA:
2.1		 4qd3A-3lyuA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3lyu PUTATIVE HYDROGENASE
(Pyrococcus
furiosus) 		4 / 7 GLU A 206
ARG A 181
LYS A 209
TYR A 211
 None
 1.43A 4uciB-3lyuA:
undetectable		 4uciB-3lyuA:
18.07