SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3lz8 PUTATIVE CHAPERONE
DNAJ
(Klebsiella
pneumoniae) 		5 / 9 THR A 130
VAL A 168
ASP A 169
ILE A 195
VAL A 167
 None
 1.44A 2l8mA-3lz8A:
undetectable		 2l8mA-3lz8A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3lz8 PUTATIVE CHAPERONE
DNAJ
(Klebsiella
pneumoniae) 		4 / 6 GLU A 120
ILE A 121
GLU A 129
VAL A 167
 None
 1.05A 4ejwB-3lz8A:
undetectable		 4ejwB-3lz8A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3lz8 PUTATIVE CHAPERONE
DNAJ
(Klebsiella
pneumoniae) 		5 / 10 LEU A 127
VAL A 258
VAL A 167
GLY A 166
LEU A 210
 None
 1.34A 6bsiA-3lz8A:
undetectable		 6bsiA-3lz8A:
12.06