SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3lza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
denitrificans) 		4 / 7 LEU A  28
LEU A  30
MET A  99
LEU A 129
 None
 1.05A 1kt3A-3lzaA:
undetectable		 1kt3A-3lzaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
denitrificans) 		3 / 3 GLY A 107
PRO A 108
GLN A 111
 None
 0.56A 4oltB-3lzaA:
undetectable		 4oltB-3lzaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
denitrificans) 		5 / 12 ILE A 100
GLY A 101
ASN A  86
PRO A 124
ALA A 122
 None
 1.01A 4rvgA-3lzaA:
undetectable		 4rvgA-3lzaA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
denitrificans) 		5 / 9 LEU A 138
VAL A 142
ILE A  33
LEU A  44
MET A  99
 None
 1.35A 5og9A-3lzaA:
undetectable		 5og9A-3lzaA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
denitrificans) 		4 / 8 ILE A  69
GLN A 141
THR A 127
VAL A 126
 None
 1.04A 6fbvC-3lzaA:
undetectable		 6fbvC-3lzaA:
8.07