SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 10 LEU A 309
GLU A 291
LEU A 294
PHE A 227
GLY A 255
 None
 1.41A 1mjqC-3m0oA:
undetectable
1mjqD-3m0oA:
undetectable		 1mjqC-3m0oA:
19.05
1mjqD-3m0oA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 ALA A 194
ASP A 195
ASP A   5
VAL A  32
ILE A   7
 None
 1.26A 2o4lA-3m0oA:
undetectable		 2o4lA-3m0oA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 6 PHE A 325
PHE A 342
GLY A 352
GLY A 354
 None
FAD  A 400 (-4.8A)
None
None
 0.97A 2qr2A-3m0oA:
undetectable
2qr2B-3m0oA:
2.3		 2qr2A-3m0oA:
23.12
2qr2B-3m0oA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 5 GLY A 352
GLY A 354
PHE A 325
PHE A 342
 None
None
None
FAD  A 400 (-4.8A)
 1.01A 2qr2A-3m0oA:
undetectable
2qr2B-3m0oA:
2.3		 2qr2A-3m0oA:
23.12
2qr2B-3m0oA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 6 PHE A 325
ILE A 327
PHE A 342
GLY A 352
GLY A 354
 None
None
FAD  A 400 (-4.8A)
None
None
 1.15A 2qx6A-3m0oA:
2.2
2qx6B-3m0oA:
undetectable		 2qx6A-3m0oA:
23.12
2qx6B-3m0oA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 6 LEU A 197
ALA A 361
LEU A 357
ALA A  18
 None
 0.98A 2vcvK-3m0oA:
undetectable		 2vcvK-3m0oA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 GLY A 263
MET A 302
THR A  87
VAL A 146
PHE A 259
 None
 1.35A 3gn8B-3m0oA:
undetectable		 3gn8B-3m0oA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		3 / 3 GLY A 341
THR A 318
ASN A 205
 None
 0.40A 3v4tD-3m0oA:
undetectable		 3v4tD-3m0oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 7 ASN A 124
GLU A 122
ILE A 123
ASN A 135
 None
 1.11A 4d39B-3m0oA:
undetectable		 4d39B-3m0oA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 GLY A 352
GLY A 354
PHE A 325
ILE A 327
PHE A 342
 None
None
None
None
FAD  A 400 (-4.8A)
 1.18A 4fglA-3m0oA:
2.4
4fglB-3m0oA:
undetectable		 4fglA-3m0oA:
24.14
4fglB-3m0oA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 11 PHE A 325
ILE A 327
PHE A 342
GLY A 352
GLY A 354
 None
None
FAD  A 400 (-4.8A)
None
None
 1.21A 4fglA-3m0oA:
2.3
4fglB-3m0oA:
undetectable		 4fglA-3m0oA:
24.14
4fglB-3m0oA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 8 SER A 258
ASN A 237
THR A  48
GLY A 255
 None
 1.00A 4fo4A-3m0oA:
undetectable		 4fo4A-3m0oA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 GLY A 263
LEU A 298
MET A 302
THR A  87
PHE A 259
 None
 1.48A 4p6xG-3m0oA:
undetectable		 4p6xG-3m0oA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		3 / 3 MET A  16
ASP A  36
PHE A  35
 None
None
FAD  A 400 (-4.7A)
 1.00A 4xeyA-3m0oA:
undetectable		 4xeyA-3m0oA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		3 / 3 MET A  16
ASP A  36
PHE A  35
 None
None
FAD  A 400 (-4.7A)
 1.00A 4xeyB-3m0oA:
undetectable		 4xeyB-3m0oA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 GLY A 352
GLY A 354
PHE A 325
ILE A 327
PHE A 342
 None
None
None
None
FAD  A 400 (-4.8A)
 1.16A 4zvmA-3m0oA:
undetectable
4zvmB-3m0oA:
undetectable		 4zvmA-3m0oA:
23.12
4zvmB-3m0oA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		4 / 8 PRO A  38
LEU A  75
ILE A  83
LEU A  31
 None
 0.90A 5ieoA-3m0oA:
undetectable		 5ieoA-3m0oA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 LEU A  64
VAL A 356
GLY A 354
SER A 351
LEU A  71
 None
 1.01A 5ikrA-3m0oA:
undetectable		 5ikrA-3m0oA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 10 GLY A 352
GLY A 354
PHE A 325
ILE A 327
PHE A 342
 None
None
None
None
FAD  A 400 (-4.8A)
 1.12A 5lbtA-3m0oA:
undetectable
5lbtB-3m0oA:
undetectable		 5lbtA-3m0oA:
22.88
5lbtB-3m0oA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		6 / 12 GLY A  88
THR A  87
GLY A 145
PRO A 242
LEU A 117
ASN A 143
 None
 1.32A 5ybbA-3m0oA:
undetectable		 5ybbA-3m0oA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3m0o MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
B-0618) 		5 / 12 PRO A 257
VAL A 146
ILE A 130
ILE A  50
PHE A 140
 None
None
None
FAD  A 400 (-4.0A)
None
 1.27A 6j20A-3m0oA:
undetectable		 6j20A-3m0oA:
20.74