SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 7 LEU A  40
THR A 229
ASN A  15
TYR A 218
None
None
None
SO4  A 301 (-4.7A)
1.13A 1afsA-3m0zA:
7.0
1afsA-3m0zA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 7 LEU A  40
THR A 229
ASN A  15
TYR A 218
None
None
None
SO4  A 301 (-4.7A)
1.12A 1afsB-3m0zA:
7.2
1afsB-3m0zA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
5 / 10 ASN A 114
LEU A  65
LEU A  17
TYR A 218
THR A 190
None
None
None
SO4  A 301 (-4.7A)
None
1.34A 1zucA-3m0zA:
undetectable
1zucA-3m0zA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
3 / 3 ASP A 233
ASP A 223
ASP A 194
None
0.77A 3douA-3m0zA:
undetectable
3douA-3m0zA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 8 PRO A 143
LEU A 150
ASP A 153
LYS A 152
None
1.11A 3lsfH-3m0zA:
undetectable
3lsfH-3m0zA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 7 ILE A 221
LEU A 237
ALA A  30
ALA A  31
None
0.81A 3r9tB-3m0zA:
1.7
3r9tB-3m0zA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 6 MET A 164
GLY A 166
GLU A 174
ARG A 170
None
1.38A 4bqfA-3m0zA:
undetectable
4bqfA-3m0zA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
5 / 11 GLY A 192
GLY A 191
ILE A 217
ILE A 201
PHE A 173
SO4  A 301 (-3.7A)
SO4  A 301 (-3.6A)
None
None
None
1.04A 4qoiA-3m0zA:
undetectable
4qoiB-3m0zA:
undetectable
4qoiA-3m0zA:
20.83
4qoiB-3m0zA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 8 LEU A  17
VAL A 234
LEU A 237
ILE A 221
None
0.75A 4r38A-3m0zA:
undetectable
4r38A-3m0zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
6 / 9 THR A 190
ILE A 213
LEU A  17
VAL A 234
LEU A 237
ILE A 221
None
1.07A 4r38C-3m0zA:
undetectable
4r38C-3m0zA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
5 / 10 THR A 190
ILE A 213
LEU A  17
VAL A 234
LEU A 237
None
1.19A 4r3aB-3m0zA:
undetectable
4r3aB-3m0zA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 6 GLY A  98
THR A  97
SER A  77
VAL A  95
None
1.05A 5ewuA-3m0zA:
undetectable
5ewuA-3m0zA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
3m0z PUTATIVE ALDOLASE
(Klebsiella
pneumoniae)
4 / 7 ALA A  58
ILE A  83
GLN A  86
VAL A  87
None
0.84A 6cduF-3m0zA:
undetectable
6cduJ-3m0zA:
undetectable
6cduF-3m0zA:
21.41
6cduJ-3m0zA:
21.41