SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m16'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.77A 11gsA-3m16A:
undetectable		 11gsA-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.76A 11gsB-3m16A:
undetectable		 11gsB-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 5 LEU A 122
GLU A 103
ALA A  85
LEU A 125
 None
 1.16A 1eta1-3m16A:
undetectable		 1eta1-3m16A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 5 LEU A 122
GLU A 103
ALA A  85
LEU A 125
 None
 1.11A 1eta2-3m16A:
undetectable		 1eta2-3m16A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 6 ALA A 150
GLU A 154
ILE A 138
LEU A 162
 None
 0.97A 1xvaA-3m16A:
undetectable
1xvaB-3m16A:
undetectable		 1xvaA-3m16A:
22.12
1xvaB-3m16A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 11 THR A 179
LEU A 162
GLY A 146
THR A 112
VAL A 116
 None
 1.27A 2a1nA-3m16A:
undetectable		 2a1nA-3m16A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 12 TYR A 126
GLY A  89
GLY A  23
THR A  38
ILE A 131
 None
 1.15A 2akeA-3m16A:
undetectable		 2akeA-3m16A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 12 TYR A 126
GLY A  89
GLY A  23
THR A  38
ILE A 131
 None
 1.13A 2azxA-3m16A:
undetectable		 2azxA-3m16A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 12 TYR A 126
GLY A  89
GLY A  23
THR A  38
ILE A 131
 None
 1.15A 2azxB-3m16A:
undetectable		 2azxB-3m16A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 10 ALA A 244
LEU A 266
LEU A  12
ALA A  11
VAL A  18
 None
 0.99A 2bxgB-3m16A:
undetectable		 2bxgB-3m16A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 11 TYR A 126
GLY A  89
GLY A  23
THR A  38
ILE A 131
 None
 1.17A 2dr2A-3m16A:
undetectable		 2dr2A-3m16A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.76A 2gssA-3m16A:
undetectable		 2gssA-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.76A 2gssB-3m16A:
undetectable		 2gssB-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.74A 3gssA-3m16A:
undetectable		 3gssA-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.74A 3gssB-3m16A:
undetectable		 3gssB-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.77A 3hjoA-3m16A:
undetectable		 3hjoA-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		3 / 3 THR A 237
LYS A 139
GLU A 239
 None
 0.97A 3ijdB-3m16A:
7.8		 3ijdB-3m16A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		3 / 3 LYS A 139
ILE A  28
PHE A  31
 None
 1.00A 3j7zS-3m16A:
undetectable
3j7za-3m16A:
undetectable		 3j7zS-3m16A:
19.28
3j7za-3m16A:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 10 THR A 179
LEU A 162
GLY A 146
THR A 112
VAL A 116
 None
 1.30A 3lxiA-3m16A:
undetectable		 3lxiA-3m16A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 11 THR A 179
LEU A 162
GLY A 146
THR A 112
VAL A 116
 None
 1.30A 3lxiB-3m16A:
undetectable		 3lxiB-3m16A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 11 LEU A 165
TYR A 220
ILE A 147
ALA A 173
LEU A 283
 None
 1.10A 3n8yA-3m16A:
undetectable		 3n8yA-3m16A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.81A 3n9jA-3m16A:
undetectable		 3n9jA-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.82A 3n9jB-3m16A:
undetectable		 3n9jB-3m16A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		3 / 3 ILE A 152
VAL A 116
ARG A 120
 None
 0.60A 3p73A-3m16A:
undetectable		 3p73A-3m16A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 PRO A 184
LEU A 243
LEU A 270
ILE A 216
 None
 0.92A 3u5jA-3m16A:
undetectable		 3u5jA-3m16A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 12 LEU A 162
SER A 183
ILE A 123
ILE A 138
LEU A  93
 None
 1.21A 3w67D-3m16A:
1.4		 3w67D-3m16A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 7 LEU A 316
ALA A  85
VAL A  92
ILE A  43
 None
 0.94A 3wsjB-3m16A:
undetectable		 3wsjB-3m16A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		5 / 12 LEU A 122
LEU A 125
ALA A 129
ALA A  59
THR A 102
 None
 1.07A 4fn9A-3m16A:
undetectable		 4fn9A-3m16A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		3 / 3 LYS A 118
LEU A 108
ALA A 117
 None
 0.68A 4ikiA-3m16A:
undetectable		 4ikiA-3m16A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 6 LEU A  44
ILE A  43
LEU A 316
GLU A 317
 None
 0.98A 4w5nA-3m16A:
undetectable		 4w5nA-3m16A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		4 / 8 ALA A 117
ILE A 152
ALA A 149
LEU A 153
 None
 0.70A 5te8B-3m16A:
undetectable		 5te8B-3m16A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3m16 TRANSALDOLASE
(Oleispira
antarctica) 		3 / 3 THR A 163
GLU A 154
ASN A 161
 None
 0.87A 6nj9K-3m16A:
undetectable		 6nj9K-3m16A:
24.82