SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 9 LEU A 113
LEU A  97
VAL A  77
LEU A  84
PHE A 102
 None
 1.21A 1tbfA-3m19A:
undetectable		 1tbfA-3m19A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 9 LEU A 137
LEU A 121
VAL A 101
LEU A 108
PHE A 126
 None
 1.24A 1tbfA-3m19A:
undetectable		 1tbfA-3m19A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 7 ILE A 204
TYR A 199
PHE A 174
ASP A 175
 None
 1.14A 2qebA-3m19A:
undetectable		 2qebA-3m19A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 7 ILE A 204
TYR A 199
PHE A 174
ASP A 175
 None
 1.10A 2qebB-3m19A:
undetectable		 2qebB-3m19A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 LEU A  63
LEU A 161
ILE A 145
VAL A 125
VAL A 101
 None
 1.10A 2ygnA-3m19A:
undetectable		 2ygnA-3m19A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 LEU A  65
LEU A 161
ILE A 145
VAL A 125
VAL A 101
 None
 1.00A 2ygnA-3m19A:
undetectable		 2ygnA-3m19A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 7 THR A  53
LEU A  63
LEU A  41
LEU A  39
 None
 0.94A 3bgdB-3m19A:
undetectable		 3bgdB-3m19A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 7 THR A  53
LEU A  65
LEU A  46
LEU A  41
 None
 0.87A 3bgdB-3m19A:
undetectable		 3bgdB-3m19A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 6 LEU A 113
PHE A 126
ALA A 149
LEU A 142
 None
 0.94A 3t3zA-3m19A:
undetectable		 3t3zA-3m19A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 6 LEU A 137
PHE A 150
ALA A 173
LEU A 166
 None
 0.98A 3t3zA-3m19A:
undetectable		 3t3zA-3m19A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 6 LEU A 113
PHE A 126
ALA A 149
LEU A 142
 None
 0.95A 3t3zB-3m19A:
undetectable		 3t3zB-3m19A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 6 LEU A 137
PHE A 150
ALA A 173
LEU A 166
 None
 0.99A 3t3zB-3m19A:
undetectable		 3t3zB-3m19A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 6 LEU A 113
PHE A 126
ALA A 149
LEU A 142
 None
 0.99A 3t3zD-3m19A:
undetectable		 3t3zD-3m19A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 4 ASN A  91
ALA A  90
GLY A 115
THR A 139
 None
 1.34A 4bboC-3m19A:
undetectable		 4bboC-3m19A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 5 THR A  36
THR A  53
LEU A  65
LEU A  63
 None
 1.12A 4lvcB-3m19A:
undetectable		 4lvcB-3m19A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 PHE A  78
ILE A  32
LEU A  49
LEU A  65
LEU A  41
 None
 1.23A 4xumA-3m19A:
undetectable		 4xumA-3m19A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 LEU A 129
LEU A  94
PHE A 102
PHE A  78
LEU A  49
 None
 1.22A 5iepA-3m19A:
undetectable		 5iepA-3m19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 4 GLN A 181
THR A 182
GLU A 134
LEU A 153
 None
 1.48A 5m66A-3m19A:
undetectable		 5m66A-3m19A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		3 / 3 THR A  36
THR A  53
LEU A  65
 None
 0.49A 5m66D-3m19A:
undetectable		 5m66D-3m19A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 8 VAL A 101
GLY A  88
LEU A 111
THR A  86
 None
 0.98A 5sxqA-3m19A:
undetectable		 5sxqA-3m19A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 8 VAL A 101
GLY A  88
LEU A 111
THR A  86
 None
 0.95A 5syjB-3m19A:
undetectable		 5syjB-3m19A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		5 / 12 ASN A  68
ASN A  92
LEU A  65
ASN A  64
GLY A  22
 None
 1.10A 6dwnA-3m19A:
undetectable		 6dwnA-3m19A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3m19 VARIABLE LYMPHOCYTE
RECEPTOR A DIVERSITY
REGION
(Petromyzon
marinus) 		4 / 5 ILE A  32
THR A  36
THR A  53
LEU A  65
 None
 0.87A 6f3mD-3m19A:
undetectable		 6f3mD-3m19A:
20.68