SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 GLY A  18
VAL A  10
ILE A 232
ALA A  24
ALA A  25
 None
 0.83A 1bx4A-3m1aA:
6.2		 1bx4A-3m1aA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 ILE A  21
GLY A  12
ALA A  20
ASP A  59
LEU A  58
 None
 1.30A 1i9gA-3m1aA:
6.8		 1i9gA-3m1aA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 GLU A  97
THR A  98
THR A  99
ARG A 211
PHE A 196
 None
None
None
None
NA  A 282 ( 4.9A)
 1.13A 2einA-3m1aA:
0.0
2einB-3m1aA:
0.0
2einT-3m1aA:
0.0		 2einA-3m1aA:
20.88
2einB-3m1aA:
21.40
2einT-3m1aA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 7 VAL A 134
SER A 132
LEU A 245
THR A 241
 None
 1.15A 2f78B-3m1aA:
undetectable		 2f78B-3m1aA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 7 VAL A  84
LEU A 247
THR A 241
SER A 132
 None
 1.06A 2hdnF-3m1aA:
5.1
2hdnG-3m1aA:
undetectable
2hdnH-3m1aA:
4.3		 2hdnF-3m1aA:
24.93
2hdnG-3m1aA:
8.37
2hdnH-3m1aA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 LEU A  74
GLN A 124
VAL A  82
ARG A 128
THR A  35
 None
 1.20A 2q7lA-3m1aA:
undetectable		 2q7lA-3m1aA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 5 PHE A 148
PHE A 184
PHE A 139
ILE A  21
 None
 1.29A 2v0mD-3m1aA:
undetectable		 2v0mD-3m1aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		3 / 3 ASP A 250
PHE A 139
LEU A 255
 None
 0.70A 2zi9A-3m1aA:
3.5		 2zi9A-3m1aA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 GLU A  97
THR A  98
THR A  99
ARG A 211
PHE A 196
 None
None
None
None
NA  A 282 ( 4.9A)
 1.10A 2zxwA-3m1aA:
0.5
2zxwB-3m1aA:
undetectable
2zxwT-3m1aA:
undetectable		 2zxwA-3m1aA:
20.88
2zxwB-3m1aA:
21.40
2zxwT-3m1aA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 THR A 241
LEU A 247
PHE A  17
VAL A 179
ALA A 230
 None
 1.43A 3u9fD-3m1aA:
undetectable
3u9fE-3m1aA:
undetectable		 3u9fD-3m1aA:
19.06
3u9fE-3m1aA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 GLY A 223
PRO A 222
LEU A 247
PRO A 181
VAL A 179
 None
 1.01A 4gc9A-3m1aA:
4.9		 4gc9A-3m1aA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 MET A 125
LEU A 122
ALA A 166
SER A 162
LEU A 165
 None
 1.21A 4m11A-3m1aA:
undetectable		 4m11A-3m1aA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 LEU A  74
GLN A 124
VAL A  82
ARG A 128
THR A  35
 None
 1.09A 4oktA-3m1aA:
undetectable		 4oktA-3m1aA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.43A 4qvlH-3m1aA:
undetectable
4qvlN-3m1aA:
undetectable		 4qvlH-3m1aA:
22.82
4qvlN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 4qvmV-3m1aA:
undetectable
4qvmb-3m1aA:
undetectable		 4qvmV-3m1aA:
22.82
4qvmb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qvmH-3m1aA:
undetectable
4qvmN-3m1aA:
undetectable		 4qvmH-3m1aA:
22.82
4qvmN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qvpV-3m1aA:
undetectable
4qvpb-3m1aA:
undetectable		 4qvpV-3m1aA:
22.82
4qvpb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.38A 4qvpH-3m1aA:
undetectable
4qvpN-3m1aA:
undetectable		 4qvpH-3m1aA:
22.82
4qvpN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qvqV-3m1aA:
undetectable
4qvqb-3m1aA:
undetectable		 4qvqV-3m1aA:
22.82
4qvqb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qvqH-3m1aA:
undetectable
4qvqN-3m1aA:
undetectable		 4qvqH-3m1aA:
22.82
4qvqN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qvvV-3m1aA:
0.0
4qvvb-3m1aA:
0.0		 4qvvV-3m1aA:
22.82
4qvvb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.42A 4qvvH-3m1aA:
undetectable
4qvvN-3m1aA:
undetectable		 4qvvH-3m1aA:
22.82
4qvvN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qvwV-3m1aA:
undetectable
4qvwb-3m1aA:
undetectable		 4qvwV-3m1aA:
22.82
4qvwb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qvwH-3m1aA:
undetectable
4qvwN-3m1aA:
undetectable		 4qvwH-3m1aA:
22.82
4qvwN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 THR A  35
ALA A  36
ALA A  55
VAL A  32
GLY A  18
 None
 0.93A 4qvyK-3m1aA:
undetectable
4qvyL-3m1aA:
undetectable		 4qvyK-3m1aA:
21.35
4qvyL-3m1aA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 THR A  35
ALA A  36
ALA A  55
VAL A  32
GLY A  18
 None
 0.93A 4qvyY-3m1aA:
undetectable
4qvyZ-3m1aA:
undetectable		 4qvyY-3m1aA:
21.35
4qvyZ-3m1aA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qw0V-3m1aA:
undetectable
4qw0b-3m1aA:
undetectable		 4qw0V-3m1aA:
22.82
4qw0b-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qw0H-3m1aA:
undetectable
4qw0N-3m1aA:
undetectable		 4qw0H-3m1aA:
22.82
4qw0N-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qw1V-3m1aA:
undetectable
4qw1b-3m1aA:
undetectable		 4qw1V-3m1aA:
22.82
4qw1b-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 4qw1H-3m1aA:
undetectable
4qw1N-3m1aA:
undetectable		 4qw1H-3m1aA:
22.82
4qw1N-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 4qw3V-3m1aA:
undetectable
4qw3b-3m1aA:
undetectable		 4qw3V-3m1aA:
22.82
4qw3b-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 4qw3H-3m1aA:
undetectable
4qw3N-3m1aA:
undetectable		 4qw3H-3m1aA:
22.82
4qw3N-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qwuV-3m1aA:
undetectable
4qwub-3m1aA:
undetectable		 4qwuV-3m1aA:
22.82
4qwub-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 4qwuH-3m1aA:
undetectable
4qwuN-3m1aA:
undetectable		 4qwuH-3m1aA:
22.82
4qwuN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 5 ALA A  53
ARG A  19
ALA A  25
GLU A  23
 None
 1.12A 5a06C-3m1aA:
2.2
5a06D-3m1aA:
1.6		 5a06C-3m1aA:
23.89
5a06D-3m1aA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 9 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 5cz7V-3m1aA:
0.0
5cz7b-3m1aA:
0.0		 5cz7V-3m1aA:
22.82
5cz7b-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 5cz7H-3m1aA:
undetectable
5cz7N-3m1aA:
undetectable		 5cz7H-3m1aA:
22.82
5cz7N-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.42A 5d0xV-3m1aA:
undetectable
5d0xb-3m1aA:
undetectable		 5d0xV-3m1aA:
22.82
5d0xb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.42A 5d0xH-3m1aA:
undetectable
5d0xN-3m1aA:
undetectable		 5d0xH-3m1aA:
22.82
5d0xN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 GLY A  18
VAL A  10
ILE A 232
ALA A  24
ALA A  25
 None
 0.84A 5kb6A-3m1aA:
6.0		 5kb6A-3m1aA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 GLY A  18
VAL A  10
ILE A 232
ALA A  24
ALA A  25
 None
 0.87A 5kb6B-3m1aA:
5.5		 5kb6B-3m1aA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 GLY A  34
ASP A  59
VAL A  60
THR A  61
VAL A  84
 None
 1.00A 5kocA-3m1aA:
5.0		 5kocA-3m1aA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.41A 5l5fV-3m1aA:
undetectable
5l5fb-3m1aA:
undetectable		 5l5fV-3m1aA:
22.82
5l5fb-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.40A 5l5fH-3m1aA:
undetectable
5l5fN-3m1aA:
0.0		 5l5fH-3m1aA:
22.82
5l5fN-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 5l66V-3m1aA:
undetectable
5l66b-3m1aA:
undetectable		 5l66V-3m1aA:
22.82
5l66b-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 SER A 149
THR A  98
THR A  99
ALA A 150
THR A 154
 None
 1.39A 5l66H-3m1aA:
undetectable
5l66N-3m1aA:
undetectable		 5l66H-3m1aA:
22.82
5l66N-3m1aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 THR A  99
ALA A  94
GLY A  93
ALA A 150
LEU A 109
 None
 0.99A 5lf7H-3m1aA:
undetectable
5lf7I-3m1aA:
undetectable		 5lf7H-3m1aA:
23.99
5lf7I-3m1aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 11 THR A  99
ALA A  94
GLY A  93
ALA A 150
LEU A 109
 None
 1.00A 5lf7V-3m1aA:
undetectable
5lf7W-3m1aA:
undetectable		 5lf7V-3m1aA:
23.99
5lf7W-3m1aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 6 ARG A 116
ALA A 115
PRO A 114
GLU A 108
 None
 1.33A 5odqA-3m1aA:
2.6		 5odqA-3m1aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 12 VAL A  32
LEU A  45
VAL A  10
GLY A  18
ILE A  21
 None
 0.99A 5vopA-3m1aA:
2.0		 5vopA-3m1aA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		5 / 10 GLU A  97
THR A  98
THR A  99
ARG A 211
PHE A 196
 None
None
None
None
NA  A 282 ( 4.9A)
 1.07A 5x1bA-3m1aA:
0.0
5x1bB-3m1aA:
0.0
5x1bT-3m1aA:
0.0		 5x1bA-3m1aA:
20.88
5x1bB-3m1aA:
21.40
5x1bT-3m1aA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3m1a PUTATIVE
DEHYDROGENASE
(Streptomyces
avermitilis) 		4 / 8 HIS A 258
PHE A 145
SER A 138
LEU A 213
 None
 1.07A 5y2tB-3m1aA:
undetectable		 5y2tB-3m1aA:
undetectable