SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3m1c ENVELOPE
GLYCOPROTEIN H
ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		5 / 10 LEU B  72
VAL A  94
ILE B  70
LEU A 114
LEU B 107
 None
 1.20A 1cqpA-3m1cB:
undetectable
1cqpB-3m1cB:
undetectable		 1cqpA-3m1cB:
16.91
1cqpB-3m1cB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		3 / 3 TRP A 244
ARG A 266
THR A 243
 None
 0.99A 1df7A-3m1cA:
undetectable		 1df7A-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 ILE A 667
ALA A 732
LEU A 729
LEU A 790
ARG A 736
 None
 1.06A 1g5yB-3m1cA:
undetectable		 1g5yB-3m1cA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 PHE A 411
LEU A 418
GLY A 384
ALA A 383
LEU A 254
 None
 1.14A 1igxA-3m1cA:
undetectable		 1igxA-3m1cA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		3 / 3 ALA A 413
HIS A 414
VAL A 417
 None
 0.51A 1lquB-3m1cA:
undetectable		 1lquB-3m1cA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.97A 1wmqA-3m1cA:
undetectable		 1wmqA-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.96A 1wmqB-3m1cA:
undetectable		 1wmqB-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.95A 1wpuA-3m1cA:
undetectable		 1wpuA-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.95A 1wpuB-3m1cA:
undetectable		 1wpuB-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.96A 1wrqA-3m1cA:
undetectable		 1wrqA-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 ARG A 545
ILE A 549
GLY A 546
ALA A 543
 None
 0.97A 1wrqB-3m1cA:
undetectable		 1wrqB-3m1cA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 11 GLY A 428
ILE A 276
SER A 281
ALA A 260
ALA A 261
 None
 0.98A 1x7pA-3m1cA:
undetectable
1x7pB-3m1cA:
undetectable		 1x7pA-3m1cA:
19.86
1x7pB-3m1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		3 / 3 SER A 389
VAL A 438
LEU A 254
 None
 0.54A 1yajG-3m1cA:
undetectable		 1yajG-3m1cA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 LEU A 412
LEU A 409
LEU A 214
LEU A 449
PHE A 393
 None
 1.18A 1zucB-3m1cA:
undetectable		 1zucB-3m1cA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 6 LEU A 409
LEU A 412
LEU A 449
LEU A 456
 None
 0.96A 2ab2A-3m1cA:
undetectable		 2ab2A-3m1cA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 5 LEU A 781
LEU A 688
ILE A 713
ALA A 778
 None
 0.74A 2i2zA-3m1cA:
2.5		 2i2zA-3m1cA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 8 ARG A 424
ARG A 527
PRO A 666
SER A 672
 None
 1.15A 2qd2A-3m1cA:
undetectable		 2qd2A-3m1cA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 LEU A 227
ILE A 403
LEU A 222
PHE A 393
ARG A 446
 None
 1.11A 2qo6A-3m1cA:
undetectable		 2qo6A-3m1cA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 10 VAL A 434
PHE A 256
SER A 277
GLY A 425
ALA A 422
 None
 1.25A 2x2iB-3m1cA:
undetectable		 2x2iB-3m1cA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		4 / 7 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.85A 3bjwB-3m1cB:
undetectable		 3bjwB-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		4 / 7 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.81A 3bjwF-3m1cB:
undetectable		 3bjwF-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		4 / 7 VAL B  61
ILE B  67
GLY B  69
ARG B  86
 None
 0.90A 3bjwH-3m1cB:
undetectable		 3bjwH-3m1cB:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3m1c ENVELOPE
GLYCOPROTEIN H
ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		5 / 12 LEU A 310
ALA A 164
VAL B 145
GLY A 325
VAL A 246
 None
 1.15A 3c6gB-3m1cA:
undetectable		 3c6gB-3m1cA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 ASN A 395
GLY A 273
PHE A 391
SER A 388
THR A 251
 None
 1.09A 3iv6A-3m1cA:
undetectable		 3iv6A-3m1cA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3m1c ENVELOPE
GLYCOPROTEIN H
ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		4 / 6 LEU B  72
ILE B  70
CYH A  90
PHE A  89
 None
 1.01A 3ko0S-3m1cB:
undetectable		 3ko0S-3m1cB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		3 / 3 ARG A 527
LEU A 640
THR A 551
 None
 0.70A 3oxcA-3m1cA:
undetectable		 3oxcA-3m1cA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 PRO A 588
LEU A 510
LEU A 505
ILE A 549
PHE A 770
 None
 1.20A 4a79B-3m1cA:
undetectable		 4a79B-3m1cA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 8 THR A 551
LEU A 548
VAL A 733
VAL A 746
 None
 0.86A 4em2A-3m1cA:
1.5		 4em2A-3m1cA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		4 / 8 ASP A 565
VAL A 627
PHE A 580
LEU A 582
 None
 1.06A 4f8hB-3m1cA:
undetectable
4f8hC-3m1cA:
undetectable		 4f8hB-3m1cA:
18.64
4f8hC-3m1cA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		3 / 3 TYR A 701
ARG A 711
HIS A 709
 None
 1.22A 4fubA-3m1cA:
undetectable		 4fubA-3m1cA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		3 / 3 TYR B  64
ARG B 122
HIS B 109
 None
 1.24A 4fubA-3m1cB:
undetectable		 4fubA-3m1cB:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		3 / 3 TYR B 126
ARG B 122
HIS B 109
 None
 0.98A 4fubA-3m1cB:
undetectable		 4fubA-3m1cB:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 LEU A 631
VAL A 627
ALA A 568
PHE A 580
LEU A 382
 None
 1.49A 4iarA-3m1cA:
2.8		 4iarA-3m1cA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 11 LEU A 531
GLY A 420
LEU A 421
ALA A 524
PHE A 363
 None
 1.35A 4wnuC-3m1cA:
undetectable		 4wnuC-3m1cA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 9 ARG A 517
ALA A 518
LEU A 472
GLY A 473
LEU A 467
 None
 1.00A 5dqfA-3m1cA:
2.8		 5dqfA-3m1cA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 11 GLN A 475
LEU A 476
LEU A 412
ALA A 413
LEU A 209
 None
 1.20A 5ji0A-3m1cA:
undetectable		 5ji0A-3m1cA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 12 MET A 514
ALA A 471
HIS A 470
LEU A 472
ALA A 469
 None
 1.09A 5k9dA-3m1cA:
undetectable		 5k9dA-3m1cA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3m1c ENVELOPE
GLYCOPROTEIN H
(Human
alphaherpesvirus
2) 		5 / 10 ILE A 287
LEU A 295
PHE A 322
GLY A 270
PHE A 271
 None
 1.12A 5mxbA-3m1cA:
0.6		 5mxbA-3m1cA:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3m1c ENVELOPE
GLYCOPROTEIN L
(Human
alphaherpesvirus
2) 		5 / 9 PHE B  71
ASP B  68
VAL B  61
SER B  60
ASP B  63
 None
 1.42A 6c2mD-3m1cB:
undetectable		 6c2mD-3m1cB:
20.00