SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 ASP A  29
HIS A  51
ASP A 157
 None
GOL  A 362 (-3.9A)
None
 0.90A 1nw5A-3m1gA:
undetectable		 1nw5A-3m1gA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 4 SER A  87
ILE A  86
VAL A 147
THR A 134
 None
 1.24A 1u70A-3m1gA:
undetectable		 1u70A-3m1gA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 5 TYR A 276
ILE A 238
ARG A 327
GLY A 275
 None
 1.32A 2du8J-3m1gA:
undetectable		 2du8J-3m1gA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 ARG A 264
ASP A 253
ASP A 317
 None
 0.84A 2ejtA-3m1gA:
undetectable		 2ejtA-3m1gA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A  80
LEU A 138
ASN A 159
LEU A 173
ILE A 156
 None
None
None
None
GOL  A 364 (-4.6A)
 1.18A 2uxoB-3m1gA:
undetectable		 2uxoB-3m1gA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 ALA A 219
GLU A 192
ARG A 199
LEU A 273
MET A 270
 None
 1.15A 3hm1A-3m1gA:
undetectable		 3hm1A-3m1gA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 GLY A 285
THR A 289
ILE A 238
ARG A  77
LEU A  79
 None
 1.29A 3iv6C-3m1gA:
undetectable		 3iv6C-3m1gA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 5 ILE A  86
PHE A 158
ASP A 157
GLU A 161
 None
 1.13A 3kp6A-3m1gA:
undetectable
3kp6B-3m1gA:
1.1		 3kp6A-3m1gA:
18.13
3kp6B-3m1gA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 5 VAL A  74
ARG A  77
GLU A 349
LEU A  90
 None
 1.38A 4hojA-3m1gA:
14.9		 4hojA-3m1gA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 VAL A 193
TRP A 222
LEU A 227
LEU A 233
 None
 1.03A 4jtrA-3m1gA:
undetectable		 4jtrA-3m1gA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		5 / 11 LEU A  80
ALA A 170
PRO A 171
ILE A 345
ASP A 288
 None
 1.23A 4uuuB-3m1gA:
undetectable		 4uuuB-3m1gA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A 135
HIS A  71
VAL A  74
 None
 0.55A 5jmnC-3m1gA:
undetectable		 5jmnC-3m1gA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		6 / 12 LEU A 341
THR A 340
ALA A 170
GLY A 343
LEU A 173
LEU A  79
 None
 1.40A 5nfjA-3m1gA:
undetectable		 5nfjA-3m1gA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 THR A 155
TRP A  69
HIS A  95
LEU A  79
 None
 1.20A 5x1bA-3m1gA:
undetectable
5x1bC-3m1gA:
undetectable
5x1bP-3m1gA:
undetectable		 5x1bA-3m1gA:
20.95
5x1bC-3m1gA:
19.40
5x1bP-3m1gA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 THR A 155
TRP A  69
HIS A  95
LEU A  79
 None
 1.16A 6nmfA-3m1gA:
undetectable
6nmfC-3m1gA:
undetectable
6nmfP-3m1gA:
undetectable		 6nmfA-3m1gA:
20.95
6nmfC-3m1gA:
19.40
6nmfP-3m1gA:
19.40