SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 6 GLY A1437
THR A1457
THR A1456
ILE A1472
 None
 0.92A 1gtnD-3m1hA:
undetectable
1gtnE-3m1hA:
undetectable		 1gtnD-3m1hA:
20.00
1gtnE-3m1hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 7 GLY A1437
THR A1457
THR A1456
ILE A1472
 None
 0.95A 1gtnF-3m1hA:
undetectable
1gtnG-3m1hA:
undetectable		 1gtnF-3m1hA:
20.00
1gtnG-3m1hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 7 GLY A1437
THR A1457
THR A1456
ILE A1472
 None
 0.98A 1gtnJ-3m1hA:
undetectable
1gtnK-3m1hA:
1.8		 1gtnJ-3m1hA:
20.00
1gtnK-3m1hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		3 / 3 ASP A1531
ASN A1534
THR A1576
 NA  A2004 ( 4.4A)
None
None
 0.69A 2q63B-3m1hA:
undetectable		 2q63B-3m1hA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 6 PHE A1581
ALA A1580
THR A1494
LEU A1572
 None
 0.83A 3t3zA-3m1hA:
undetectable		 3t3zA-3m1hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 6 PHE A1581
ALA A1580
THR A1494
LEU A1572
 None
 0.83A 3t3zB-3m1hA:
undetectable		 3t3zB-3m1hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 5 PHE A1581
ALA A1580
THR A1494
LEU A1572
 None
 0.81A 3t3zC-3m1hA:
undetectable		 3t3zC-3m1hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 6 PHE A1581
ALA A1580
THR A1494
LEU A1572
 None
 0.88A 3t3zD-3m1hA:
undetectable		 3t3zD-3m1hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		5 / 11 PHE A1584
ASN A1490
GLY A1585
ALA A1536
ASN A1537
 None
CA  A2001 (-2.9A)
None
None
None
 1.34A 4a6nA-3m1hA:
undetectable		 4a6nA-3m1hA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		4 / 7 GLU A1428
GLU A1432
TRP A1454
THR A1456
 None
NA  A2003 ( 4.7A)
None
None
 1.32A 4uacA-3m1hA:
undetectable		 4uacA-3m1hA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		3 / 3 ASP A1596
GLU A1428
SER A1464
 CA  A2002 ( 4.7A)
None
None
 0.77A 5bw4B-3m1hA:
undetectable		 5bw4B-3m1hA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		5 / 12 ALA A1532
ASP A1446
ALA A1447
ASP A1489
TYR A1491
 None
CA  A2001 (-3.0A)
None
None
None
 1.12A 5kvaA-3m1hA:
undetectable		 5kvaA-3m1hA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3m1h LYSINE SPECIFIC
CYSTEINE PROTEASE
(Porphyromonas
gingivalis) 		5 / 12 ALA A1532
ASP A1446
ALA A1447
ASP A1489
TYR A1491
 None
CA  A2001 (-3.0A)
None
None
None
 1.19A 5kvaB-3m1hA:
undetectable		 5kvaB-3m1hA:
19.87