SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2LBD_A_REAA500_1 (RETINOIC ACID RECEPTOR GAMMA)	3m1i	RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1 (Saccharomyces cerevisiae)	5 / 12	PHE B 174 MET B 126 ARG B 123 ILE B 124 GLY B 107	None	1.29A	2lbdA-3m1iB: undetectable	2lbdA-3m1iB: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	3m1i	RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1 (Saccharomyces cerevisiae)	3 / 3	CYH B 160 PHE B 172 PHE B 174	None	0.78A	3cr5X-3m1iB: undetectable	3cr5X-3m1iB: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_1 (DIHYDROPTEROATE SYNTHASE DHPS)	3m1i	RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1 (Saccharomyces cerevisiae)	3 / 3	LYS B 104 ASN B 149 ASP B 97	None	0.85A	4o1eA-3m1iB: undetectable	4o1eA-3m1iB: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3m1i	RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1 (Saccharomyces cerevisiae)	5 / 12	VAL B 157 CYH B 111 ALA B 91 LEU B 93 THR B 173	None	1.26A	4x1kA-3m1iB: undetectable 4x1kB-3m1iB: undetectable	4x1kA-3m1iB: 19.07 4x1kB-3m1iB: 17.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2LBD_A_REAA500_1","RETINOIC ACID RECEPTOR GAMMA","3m1i","RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1","Saccharomyces cerevisiae",5,"PHE B 174;MET B 126;ARG B 123;ILE B 124;GLY B 107","None","1.29A","2lbdA-3m1iB:undetectable","2lbdA-3m1iB:19.71"],["3CR5_X_PNTX95_0","PROTEIN S100-B","3m1i","RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1","Saccharomyces cerevisiae",3,"CYH B 160;PHE B 172;PHE B 174","None","0.78A","3cr5X-3m1iB:undetectable","3cr5X-3m1iB:21.39"],["4O1E_A_C2FA3000_1","DIHYDROPTEROATE SYNTHASE DHPS","3m1i","RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1","Saccharomyces cerevisiae",3,"LYS B 104;ASN B 149;ASP B  97","None","0.85A","4o1eA-3m1iB:undetectable","4o1eA-3m1iB:21.43"],["4X1K_B_LOCB502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","3m1i","RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 1","Saccharomyces cerevisiae",5,"VAL B 157;CYH B 111;ALA B  91;LEU B  93;THR B 173","None","1.26A","4x1kA-3m1iB:undetectable;4x1kB-3m1iB:undetectable","4x1kA-3m1iB:19.07;4x1kB-3m1iB:17.14"]]