SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 431
TYR A 430
LEU A 181
VAL A 189
 None
 1.02A 1dz4A-3m1lA:
undetectable		 1dz4A-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 PHE A 431
TYR A 430
THR A 177
LEU A 181
VAL A 189
 None
 1.13A 1dz8A-3m1lA:
undetectable		 1dz8A-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 366
LEU A 320
LEU A 324
PRO A 323
ALA A 387
 None
 1.19A 1gseA-3m1lA:
undetectable		 1gseA-3m1lA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.05A 1t85A-3m1lA:
undetectable		 1t85A-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
LEU A 181
 None
 1.07A 1t87A-3m1lA:
undetectable		 1t87A-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 7 PHE A 431
TYR A 430
THR A 177
LEU A 181
VAL A 189
 None
 1.10A 1t87B-3m1lA:
undetectable		 1t87B-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		6 / 10 GLY A 220
ALA A 222
ASP A 244
ASP A 267
VAL A 268
VAL A 318
 None
 0.58A 1uayB-3m1lA:
21.9		 1uayB-3m1lA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 387
ILE A 444
ALA A 389
ARG A 445
ILE A 370
 None
 1.00A 1ve3A-3m1lA:
7.1		 1ve3A-3m1lA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 387
ILE A 444
ALA A 389
ARG A 445
ILE A 370
 None
 0.92A 1ve3B-3m1lA:
7.3		 1ve3B-3m1lA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.02A 1yrcA-3m1lA:
undetectable		 1yrcA-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 1yrdA-3m1lA:
undetectable		 1yrdA-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 LEU A  49
GLY A 101
PRO A 108
VAL A 109
 None
 0.79A 2aojA-3m1lA:
undetectable		 2aojA-3m1lA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 102
PHE A 106
LEU A 141
LEU A 160
ALA A 159
 None
 1.05A 2bxpA-3m1lA:
undetectable		 2bxpA-3m1lA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.00A 2feuA-3m1lA:
undetectable		 2feuA-3m1lA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.01A 2feuB-3m1lA:
undetectable		 2feuB-3m1lA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 431
TYR A 430
LEU A 181
VAL A 189
 None
 1.00A 2m56A-3m1lA:
undetectable		 2m56A-3m1lA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 434
SER A 436
GLU A 175
PRO A 204
 None
 1.03A 2v2gA-3m1lA:
undetectable
2v2gB-3m1lA:
undetectable		 2v2gA-3m1lA:
19.50
2v2gB-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 204
PRO A 434
SER A 436
GLU A 175
 None
 1.01A 2v2gA-3m1lA:
undetectable
2v2gB-3m1lA:
undetectable		 2v2gA-3m1lA:
19.50
2v2gB-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 434
SER A 436
GLU A 175
PRO A 204
 None
 0.99A 2v2gC-3m1lA:
undetectable
2v2gD-3m1lA:
undetectable		 2v2gC-3m1lA:
19.50
2v2gD-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 204
PRO A 434
SER A 436
GLU A 175
 None
 1.05A 2v2gC-3m1lA:
undetectable
2v2gD-3m1lA:
undetectable		 2v2gC-3m1lA:
19.50
2v2gD-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 434
SER A 436
GLU A 175
PRO A 204
 None
 0.96A 2v32A-3m1lA:
undetectable
2v32B-3m1lA:
undetectable		 2v32A-3m1lA:
19.50
2v32B-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 204
PRO A 434
SER A 436
GLU A 175
 None
 0.99A 2v32A-3m1lA:
undetectable
2v32B-3m1lA:
undetectable		 2v32A-3m1lA:
19.50
2v32B-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 434
SER A 436
GLU A 175
PRO A 204
 None
 0.99A 2v32C-3m1lA:
undetectable
2v32D-3m1lA:
undetectable		 2v32C-3m1lA:
19.50
2v32D-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 434
SER A 436
GLU A 175
PRO A 204
 None
 0.99A 2v41E-3m1lA:
undetectable
2v41F-3m1lA:
undetectable		 2v41E-3m1lA:
19.50
2v41F-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 204
PRO A 434
SER A 436
GLU A 175
 None
 1.08A 2v41E-3m1lA:
undetectable
2v41F-3m1lA:
undetectable		 2v41E-3m1lA:
19.50
2v41F-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 PRO A 204
PRO A 434
SER A 436
GLU A 175
 None
 1.02A 2v41G-3m1lA:
undetectable
2v41H-3m1lA:
undetectable		 2v41G-3m1lA:
19.50
2v41H-3m1lA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 225
THR A 228
VAL A 424
GLU A 394
PRO A 390
 None
 1.29A 2yzqA-3m1lA:
undetectable		 2yzqA-3m1lA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 431
TYR A 430
LEU A 181
VAL A 189
 None
 1.04A 2zawA-3m1lA:
undetectable		 2zawA-3m1lA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 431
TYR A 430
THR A 177
LEU A 181
 None
 1.09A 2zuiA-3m1lA:
undetectable		 2zuiA-3m1lA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.05A 2zuiA-3m1lA:
undetectable		 2zuiA-3m1lA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 2zwtA-3m1lA:
undetectable		 2zwtA-3m1lA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 2zwuA-3m1lA:
undetectable		 2zwuA-3m1lA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 3fwfA-3m1lA:
undetectable		 3fwfA-3m1lA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.02A 3fwfB-3m1lA:
undetectable		 3fwfB-3m1lA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 3fwjA-3m1lA:
undetectable		 3fwjA-3m1lA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 PRO A 210
PHE A 233
ALA A 432
 None
 0.71A 3itaD-3m1lA:
undetectable		 3itaD-3m1lA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 370
ALA A 389
ALA A 296
ILE A 368
ALA A 365
 None
 1.04A 3jb1A-3m1lA:
4.8		 3jb1A-3m1lA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.01A 3l63A-3m1lA:
undetectable		 3l63A-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 211
PHE A 233
VAL A 232
ILE A 428
ALA A 425
 None
 1.13A 3mdvA-3m1lA:
undetectable		 3mdvA-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  84
GLY A  46
ALA A 156
LEU A  48
LEU A 113
 None
 1.16A 3p2kB-3m1lA:
4.4		 3p2kB-3m1lA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  84
GLY A  46
ALA A 156
LEU A  48
LEU A 113
 None
 1.06A 3p2kD-3m1lA:
5.2		 3p2kD-3m1lA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 8 ILE A 370
LEU A 374
VAL A 331
GLY A 329
 None
 0.89A 3w1wA-3m1lA:
2.7		 3w1wA-3m1lA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.02A 3wrhA-3m1lA:
undetectable		 3wrhA-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.05A 3wrjA-3m1lA:
undetectable		 3wrjA-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 3wrlA-3m1lA:
undetectable		 3wrlA-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.00A 3wrlE-3m1lA:
undetectable		 3wrlE-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.03A 3wrmA-3m1lA:
undetectable		 3wrmA-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
VAL A 189
 None
 1.01A 3wrmF-3m1lA:
undetectable		 3wrmF-3m1lA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
GLN A 138
GLY A 123
VAL A 121
 None
 0.92A 4a3uB-3m1lA:
2.3		 4a3uB-3m1lA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 431
TYR A 430
THR A 177
LEU A 181
 None
 1.07A 4l4gA-3m1lA:
undetectable		 4l4gA-3m1lA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 444
VAL A 388
LEU A 345
ILE A 229
ALA A 425
 None
 0.92A 4o1zA-3m1lA:
undetectable		 4o1zA-3m1lA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 ILE A 225
ALA A 227
THR A 255
VAL A 240
ALA A 234
 None
None
None
None
ACT  A   1 (-3.9A)
 1.21A 4oqrA-3m1lA:
undetectable		 4oqrA-3m1lA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  68
VAL A 161
LEU A  48
LEU A  70
ALA A  63
 None
 1.38A 4rtbA-3m1lA:
2.5		 4rtbA-3m1lA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR A 360
THR A 358
THR A 363
 None
 0.77A 5aoxB-3m1lA:
undetectable		 5aoxB-3m1lA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR A 360
THR A 358
THR A 363
 None
 0.78A 5aoxE-3m1lA:
undetectable		 5aoxE-3m1lA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 5 LEU A 292
PHE A 233
ILE A 343
ILE A 428
 None
 0.96A 5dzk4-3m1lA:
undetectable
5dzkg-3m1lA:
2.2
5dzkm-3m1lA:
undetectable
5dzkn-3m1lA:
undetectable		 5dzk4-3m1lA:
6.06
5dzkg-3m1lA:
19.34
5dzkm-3m1lA:
19.63
5dzkn-3m1lA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 163
GLU A  58
GLY A  54
SER A 164
ALA A 171
 None
 0.95A 5o96G-3m1lA:
2.8		 5o96G-3m1lA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		4 / 6 LEU A 281
ALA A 289
THR A 219
ASN A 294
 None
 1.03A 6f88A-3m1lA:
undetectable		 6f88A-3m1lA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 194
LEU A 174
GLY A 173
ASN A 437
ALA A  63
 None
 1.18A 6r2eE-3m1lA:
undetectable		 6r2eE-3m1lA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 PHE A 194
LEU A 174
GLY A 173
ASN A 437
ALA A  63
 None
 1.18A 6r2eF-3m1lA:
undetectable		 6r2eF-3m1lA:
22.89