SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.13A 1hrkA-3m1mA:
undetectable		 1hrkA-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.10A 1hrkB-3m1mA:
undetectable		 1hrkB-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 PRO A 336
THR A 349
ILE A 331
LEU A 320
VAL A 316
 None
 1.21A 1r30A-3m1mA:
undetectable		 1r30A-3m1mA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 PRO A 336
THR A 349
ILE A 331
LEU A 320
VAL A 316
 None
 1.21A 1r30B-3m1mA:
undetectable		 1r30B-3m1mA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 7 PHE A 353
LEU A 335
THR A 349
TYR A 352
 None
 1.19A 1rmtB-3m1mA:
undetectable		 1rmtB-3m1mA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 6 VAL A 108
SER A 150
ASP A 152
PRO A 154
 None
 1.20A 2hdnJ-3m1mA:
undetectable
2hdnK-3m1mA:
undetectable
2hdnL-3m1mA:
undetectable		 2hdnJ-3m1mA:
21.86
2hdnK-3m1mA:
6.87
2hdnL-3m1mA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.16A 2hrcA-3m1mA:
undetectable		 2hrcA-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.12A 2hrcB-3m1mA:
undetectable		 2hrcB-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 8 ILE A 109
ILE A 170
ILE A 153
VAL A 179
 None
 0.71A 2nniA-3m1mA:
undetectable		 2nniA-3m1mA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.22A 2pnjB-3m1mA:
undetectable		 2pnjB-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.09A 2po5A-3m1mA:
undetectable		 2po5A-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 11 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.07A 2po5B-3m1mA:
undetectable		 2po5B-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.14A 2po7A-3m1mA:
undetectable		 2po7A-3m1mA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.11A 2po7B-3m1mA:
undetectable		 2po7B-3m1mA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.23A 2qd4A-3m1mA:
undetectable		 2qd4A-3m1mA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.16A 2qd4B-3m1mA:
undetectable		 2qd4B-3m1mA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 11 LEU A 172
ILE A 170
PHE A 162
SER A 240
VAL A 219
 None
 1.33A 3a9eB-3m1mA:
undetectable		 3a9eB-3m1mA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.09A 3aqiB-3m1mA:
undetectable		 3aqiB-3m1mA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		3 / 3 TYR A 302
TYR A 352
GLY A 312
 None
 0.71A 3eteB-3m1mA:
undetectable
3eteD-3m1mA:
undetectable
3eteF-3m1mA:
undetectable		 3eteB-3m1mA:
22.75
3eteD-3m1mA:
22.75
3eteF-3m1mA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 9 ILE A 317
GLN A 350
ARG A 264
PHE A 353
LEU A 335
 None
 1.34A 3mjrA-3m1mA:
undetectable		 3mjrA-3m1mA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.12A 3w1wA-3m1mA:
undetectable		 3w1wA-3m1mA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 228
PHE A 162
LEU A 110
PRO A 154
TRP A 246
 None
 1.08A 3w1wB-3m1mA:
undetectable		 3w1wB-3m1mA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 12 LEU A 247
VAL A 108
PHE A 112
LEU A 224
VAL A 148
 None
 1.07A 3w68B-3m1mA:
undetectable		 3w68B-3m1mA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3m1m ORF904
(Sulfolobus
islandicus) 		5 / 9 ILE A 331
LEU A 334
ILE A 296
ILE A 295
ILE A 292
 None
 1.08A 3zosA-3m1mA:
undetectable		 3zosA-3m1mA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 5 LYS A 214
LEU A 213
GLU A 212
LEU A 209
 None
 1.31A 4k4yA-3m1mA:
2.0		 4k4yA-3m1mA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 4 LYS A 214
LEU A 213
GLU A 212
LEU A 209
 None
 1.31A 4k4yE-3m1mA:
undetectable		 4k4yE-3m1mA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3m1m ORF904
(Sulfolobus
islandicus) 		4 / 5 LYS A 214
LEU A 213
GLU A 212
LEU A 209
 None
 1.32A 4k4yI-3m1mA:
2.1		 4k4yI-3m1mA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3m1m ORF904
(Sulfolobus
islandicus) 		3 / 3 HIS A  53
GLU A  52
TRP A  49
 None
 0.97A 5odiD-3m1mA:
undetectable		 5odiD-3m1mA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3m1m ORF904
(Sulfolobus
islandicus) 		3 / 3 HIS A  53
GLU A  52
TRP A  49
 None
 0.88A 5odqD-3m1mA:
undetectable		 5odqD-3m1mA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 3m1m ORF904
(Sulfolobus
islandicus) 		3 / 3 HIS A  53
GLU A  52
TRP A  49
 None
 0.94A 5odrD-3m1mA:
undetectable		 5odrD-3m1mA:
18.29