SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 7 ASP A  45
GLY A  74
ILE A  77
ALA A  54
 None
 0.74A 1n49A-3m1pA:
undetectable		 1n49A-3m1pA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB304_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 4 GLY A  70
SER A  71
ARG A 113
PRO A  12
 None
 1.12A 4m93B-3m1pA:
0.0
4m93C-3m1pA:
undetectable		 4m93B-3m1pA:
19.05
4m93C-3m1pA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		3 / 3 ARG A 140
HIS A 138
ARG A 141
 None
None
PO4  A 154 (-3.2A)
 0.93A 5iaoC-3m1pA:
undetectable		 5iaoC-3m1pA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		3 / 3 ARG A 140
HIS A 138
ARG A 141
 None
None
PO4  A 154 (-3.2A)
 0.97A 5iaoF-3m1pA:
undetectable		 5iaoF-3m1pA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 5 THR A   9
THR A 114
HIS A  91
LEU A  89
 None
 1.26A 5utuH-3m1pA:
2.7		 5utuH-3m1pA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 5 THR A   9
THR A 115
HIS A  91
LEU A  89
 None
 1.22A 5utuH-3m1pA:
2.7		 5utuH-3m1pA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 5 ARG A 113
ALA A  69
TYR A  46
ILE A  73
 None
 1.31A 6f6sA-3m1pA:
undetectable
6f6sB-3m1pA:
undetectable		 6f6sA-3m1pA:
19.35
6f6sB-3m1pA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3m1p RIBOSE 5-PHOSPHATE
ISOMERASE
(Trypanosoma
cruzi) 		4 / 5 ARG A 113
ALA A  69
TYR A  46
ILE A  73
 None
 1.39A 6g9bA-3m1pA:
undetectable
6g9bB-3m1pA:
undetectable		 6g9bA-3m1pA:
19.35
6g9bB-3m1pA:
19.61