SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 12 ILE A  61
ALA A 301
LEU A 267
ILE A 239
THR A 298
 None
 1.07A 2bl9A-3m1rA:
undetectable		 2bl9A-3m1rA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.13A 2obvA-3m1rA:
undetectable		 2obvA-3m1rA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.07A 2p02A-3m1rA:
undetectable		 2p02A-3m1rA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 11 ILE A  61
ALA A 301
LEU A 268
ILE A 285
THR A 298
 None
 1.03A 2w9sA-3m1rA:
undetectable		 2w9sA-3m1rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 10 ILE A  61
ALA A 301
LEU A 268
ILE A 285
THR A 298
 None
 0.97A 2w9sC-3m1rA:
undetectable		 2w9sC-3m1rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 ILE A  61
ALA A 301
ILE A 285
THR A 298
 None
 0.78A 2w9sE-3m1rA:
undetectable		 2w9sE-3m1rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 10 ASP A 289
GLY A  53
ALA A  54
GLY A  59
THR A 298
 CL  A 321 ( 4.6A)
CL  A 321 ( 4.4A)
None
PEG  A 324 (-3.4A)
None
 1.07A 3el9B-3m1rA:
undetectable		 3el9B-3m1rA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 9 ASP A 289
GLY A  53
ALA A  54
GLY A  59
THR A 298
 CL  A 321 ( 4.6A)
CL  A 321 ( 4.4A)
None
PEG  A 324 (-3.4A)
None
 1.02A 3gguB-3m1rA:
undetectable		 3gguB-3m1rA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 11 ILE A 283
GLY A 282
LEU A 306
LEU A 310
ALA A 309
 None
 1.21A 3kw2A-3m1rA:
2.2		 3kw2A-3m1rA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 11 ILE A 283
GLY A 282
LEU A 306
LEU A 310
ALA A 309
 None
 1.20A 3kw2B-3m1rA:
2.5		 3kw2B-3m1rA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2U_A_ELVA397_1
(INTEGRASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 5 ASP A 242
ASP A 244
PRO A 255
GLU A 287
 CA  A 322 ( 2.9A)
CA  A 322 (-2.1A)
None
CL  A 320 ( 4.5A)
 1.24A 3l2uA-3m1rA:
0.0		 3l2uA-3m1rA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2W_A_ELVA397_1
(INTEGRASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 5 ASP A 242
ASP A 244
PRO A 255
GLU A 287
 CA  A 322 ( 2.9A)
CA  A 322 (-2.1A)
None
CL  A 320 ( 4.5A)
 1.29A 3l2wA-3m1rA:
1.2		 3l2wA-3m1rA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 5 VAL A 288
ILE A 257
MET A 211
ARG A 300
 None
 1.33A 3oezA-3m1rA:
0.0		 3oezA-3m1rA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 ASP A 150
ASP A 154
GLY A 166
TYR A 197
 CA  A 323 ( 2.7A)
CA  A 323 ( 2.5A)
None
None
 1.04A 3s3mA-3m1rA:
undetectable		 3s3mA-3m1rA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 ASP A 150
ASP A 154
GLY A 166
TYR A 197
 CA  A 323 ( 2.7A)
CA  A 323 ( 2.5A)
None
None
 1.02A 3s3nA-3m1rA:
undetectable		 3s3nA-3m1rA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 10 ILE A 239
VAL A 305
PHE A 149
ILE A 220
ILE A 274
 None
 1.33A 3um5B-3m1rA:
undetectable		 3um5B-3m1rA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 9 LEU A 307
ILE A  34
LEU A  87
ILE A  40
ILE A 122
 None
 1.01A 3zosB-3m1rA:
undetectable		 3zosB-3m1rA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		6 / 12 GLY A 124
ALA A  54
ILE A 285
ILE A 122
VAL A  42
ILE A  40
 None
 1.41A 4ax8A-3m1rA:
5.1		 4ax8A-3m1rA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		6 / 12 GLY A 124
ALA A  54
ILE A 122
LEU A  44
VAL A  42
ILE A  40
 None
 1.36A 4aztA-3m1rA:
undetectable		 4aztA-3m1rA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 12 VAL A 288
ALA A  54
GLY A 124
ASP A 293
THR A 298
 None
 1.37A 4mm4A-3m1rA:
undetectable		 4mm4A-3m1rA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 10 ASP A 289
GLY A  53
ALA A  54
GLY A  59
THR A 298
 CL  A 321 ( 4.6A)
CL  A 321 ( 4.4A)
None
PEG  A 324 (-3.4A)
None
 1.03A 4njtB-3m1rA:
undetectable		 4njtB-3m1rA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 7 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.07A 4odjA-3m1rA:
undetectable		 4odjA-3m1rA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 5 PHE A 149
SER A 132
HIS A 101
ASP A 154
 None
None
None
CA  A 323 ( 2.5A)
 1.32A 4rzvB-3m1rA:
undetectable		 4rzvB-3m1rA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		6 / 12 GLY A 124
ALA A  57
ILE A 122
LEU A  44
VAL A  42
ILE A  40
 None
 1.30A 4uw0A-3m1rA:
2.1		 4uw0A-3m1rA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.05A 5a1iA-3m1rA:
undetectable		 5a1iA-3m1rA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 7 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.05A 5a1iA-3m1rA:
undetectable		 5a1iA-3m1rA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		3 / 3 HIS A  67
SER A  23
LYS A  21
 None
 1.31A 5os7A-3m1rA:
undetectable		 5os7A-3m1rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 7 SER A  68
LEU A 307
ALA A 303
LEU A 268
 None
 1.05A 5te8A-3m1rA:
undetectable		 5te8A-3m1rA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 11 ALA A 256
ASP A 126
VAL A 305
ILE A 285
ILE A  61
 None
 1.35A 5y80A-3m1rA:
undetectable		 5y80A-3m1rA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 9 VAL A 206
HIS A 204
GLY A 180
ILE A 239
ASP A 150
 None
None
None
None
CA  A 323 ( 2.7A)
 1.35A 6c2mC-3m1rA:
undetectable		 6c2mC-3m1rA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 LEU A 292
GLU A 287
THR A 291
ASN A 165
 None
CL  A 320 ( 4.5A)
CL  A 321 (-3.3A)
CL  A 320 ( 4.7A)
 1.14A 6c71B-3m1rA:
undetectable		 6c71B-3m1rA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.06A 6fbnB-3m1rA:
undetectable		 6fbnB-3m1rA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.10A 6fboA-3m1rA:
undetectable		 6fboA-3m1rA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 8 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.07A 6fcdA-3m1rA:
undetectable		 6fcdA-3m1rA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		4 / 7 HIS A 152
ASP A 154
SER A  47
ASP A 242
 CA  A 322 (-3.4A)
CA  A 323 ( 2.5A)
None
CA  A 322 ( 2.9A)
 1.05A 6g6rA-3m1rA:
undetectable		 6g6rA-3m1rA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		3 / 3 HIS A  67
SER A  23
LYS A  21
 None
 1.31A 6gmdB-3m1rA:
undetectable		 6gmdB-3m1rA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 3m1r FORMIMIDOYLGLUTAMASE
(Bacillus
subtilis) 		5 / 12 ILE A 134
ILE A 177
VAL A 146
ILE A 178
PHE A 236
 None
 1.09A 6hlpA-3m1rA:
3.6		 6hlpA-3m1rA:
19.35