SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 MET A 269
PHE A 110
ALA A 113
ILE A 114
 None
 0.82A 1fxhA-3m1tA:
undetectable
1fxhB-3m1tA:
undetectable		 1fxhA-3m1tA:
20.43
1fxhB-3m1tA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 12 ALA A 214
GLY A 197
ASN A 166
GLU A 169
ILE A 144
 None
 1.17A 1kxhA-3m1tA:
undetectable		 1kxhA-3m1tA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 8 MET A 269
PHE A 110
ALA A 113
ILE A 114
 None
 0.71A 1pnlA-3m1tA:
undetectable
1pnlB-3m1tA:
undetectable		 1pnlA-3m1tA:
20.43
1pnlB-3m1tA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 11 LEU A  84
VAL A  66
GLY A  67
ALA A  72
LEU A  76
 None
 1.15A 2bxgA-3m1tA:
undetectable		 2bxgA-3m1tA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		3 / 3 ASP A  31
ASN A  29
THR A 191
 None
 0.70A 2pymB-3m1tA:
undetectable		 2pymB-3m1tA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		3 / 3 ASP A  31
ASN A  29
THR A 191
 None
 0.63A 2q63B-3m1tA:
undetectable		 2q63B-3m1tA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		3 / 3 PRO A 204
GLY A 215
TYR A 210
 None
 0.70A 2vouA-3m1tA:
undetectable		 2vouA-3m1tA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 6 LEU A 239
ILE A 223
ILE A 135
LEU A 213
 None
 0.96A 2xkwB-3m1tA:
undetectable		 2xkwB-3m1tA:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 4 SER A 206
GLY A 215
GLY A 197
LYS A 196
 None
 0.98A 2y4nB-3m1tA:
undetectable		 2y4nB-3m1tA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 8 SER A 138
THR A 109
ALA A 225
ALA A 224
 None
 0.85A 3ns1L-3m1tA:
undetectable		 3ns1L-3m1tA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 LEU A 194
THR A  83
ILE A  86
ASN A  28
 None
 0.93A 3p50A-3m1tA:
undetectable		 3p50A-3m1tA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 LEU A 194
THR A  83
ILE A  86
ASN A  28
 None
 0.94A 3p50B-3m1tA:
undetectable		 3p50B-3m1tA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 LEU A 194
THR A  83
ILE A  86
ASN A  28
 None
 0.93A 3p50C-3m1tA:
undetectable		 3p50C-3m1tA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 LEU A 194
THR A  83
ILE A  86
ASN A  28
 None
 0.94A 3p50D-3m1tA:
undetectable		 3p50D-3m1tA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 7 LEU A 194
THR A  83
ILE A  86
ASN A  28
 None
 0.96A 3p50E-3m1tA:
undetectable		 3p50E-3m1tA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 8 VAL A  97
TRP A 106
PRO A  14
TRP A 188
 None
 1.41A 3v35A-3m1tA:
undetectable		 3v35A-3m1tA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 12 LEU A 194
PHE A 110
GLY A 134
ALA A 130
PHE A 131
 None
 1.27A 4retA-3m1tA:
undetectable		 4retA-3m1tA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 12 LEU A  13
LEU A  16
LYS A 189
THR A 132
ALA A  93
 None
 1.14A 4x1iD-3m1tA:
undetectable		 4x1iD-3m1tA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 12 LEU A  13
LEU A  16
LYS A 189
THR A 132
ALA A  93
 None
 1.06A 4x1kA-3m1tA:
undetectable
4x1kB-3m1tA:
undetectable		 4x1kA-3m1tA:
22.30
4x1kB-3m1tA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		5 / 12 LEU A 143
PHE A 131
ILE A 114
LEU A 273
PHE A 105
 None
 1.02A 5eshA-3m1tA:
undetectable		 5eshA-3m1tA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3m1t PUTATIVE
PHOSPHOHYDROLASE
(Shewanella
amazonensis) 		4 / 6 TRP A 106
LEU A 102
GLU A 141
LEU A 142
 None
 1.38A 5xooA-3m1tA:
undetectable		 5xooA-3m1tA:
14.91