SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m1y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		3 / 3 ALA A  25
VAL A  28
TRP A  26
 None
 0.74A 1bdwA-3m1yA:
undetectable
1bdwB-3m1yA:
undetectable		 1bdwA-3m1yA:
7.34
1bdwB-3m1yA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 5 THR A  18
SER A  96
ASP A  10
SER A 117
 None
 1.12A 2hdnA-3m1yA:
undetectable
2hdnB-3m1yA:
undetectable
2hdnD-3m1yA:
2.9		 2hdnA-3m1yA:
15.13
2hdnB-3m1yA:
21.99
2hdnD-3m1yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 5 SER A 117
THR A  18
SER A  96
ASP A  10
 None
 1.09A 2hdnB-3m1yA:
undetectable
2hdnC-3m1yA:
undetectable
2hdnD-3m1yA:
2.9		 2hdnB-3m1yA:
21.99
2hdnC-3m1yA:
15.13
2hdnD-3m1yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 7 SER A 117
LEU A 127
SER A  96
ASP A  10
 None
 1.06A 2hdnF-3m1yA:
2.3
2hdnG-3m1yA:
undetectable
2hdnH-3m1yA:
undetectable		 2hdnF-3m1yA:
21.99
2hdnG-3m1yA:
15.13
2hdnH-3m1yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 6 THR A  18
SER A  96
ASP A  10
SER A 117
 None
 1.15A 2hdnI-3m1yA:
undetectable
2hdnJ-3m1yA:
2.7
2hdnL-3m1yA:
undetectable		 2hdnI-3m1yA:
15.13
2hdnJ-3m1yA:
21.99
2hdnL-3m1yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 6 SER A 117
THR A  18
SER A  96
ASP A  10
 None
 1.12A 2hdnJ-3m1yA:
2.7
2hdnK-3m1yA:
undetectable
2hdnL-3m1yA:
undetectable		 2hdnJ-3m1yA:
21.99
2hdnK-3m1yA:
15.13
2hdnL-3m1yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		4 / 8 HIS A 134
GLY A 133
ASN A 118
PHE A  95
 None
 1.27A 3ccfA-3m1yA:
3.0		 3ccfA-3m1yA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		5 / 12 VAL A 162
GLY A 163
GLY A 165
THR A  12
LEU A 200
 None
 1.02A 3dh0A-3m1yA:
2.5		 3dh0A-3m1yA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		5 / 11 ASN A 167
LEU A  50
ALA A  23
LEU A  72
PHE A  99
 CL  A 302 (-4.4A)
None
None
None
None
 1.22A 3jwqB-3m1yA:
undetectable
3jwqC-3m1yA:
undetectable		 3jwqB-3m1yA:
22.36
3jwqC-3m1yA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3m1y PHOSPHOSERINE
PHOSPHATASE (SERB)
(Helicobacter
pylori) 		5 / 10 ILE A 203
LEU A  81
GLY A 163
ALA A 180
PHE A 181
 None
 1.15A 5mxbA-3m1yA:
undetectable		 5mxbA-3m1yA:
19.34