SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		6 / 6 HIS A  44
ASN A  46
ARG A  48
ASN A  61
TRP A  68
GLU A  71
 LAT  A 999 (-3.7A)
LAT  A 999 (-4.1A)
LAT  A 999 (-3.1A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.0A)
 0.32A 3galA-3m2mA:
20.1		 3galA-3m2mA:
30.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		6 / 6 HIS A  44
ASN A  46
ARG A  48
ASN A  61
TRP A  68
GLU A  71
 LAT  A 999 (-3.7A)
LAT  A 999 (-4.1A)
LAT  A 999 (-3.1A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.0A)
 0.34A 3galB-3m2mA:
19.6		 3galB-3m2mA:
30.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		5 / 12 PHE A  30
ALA A 122
PHE A  77
LEU A 100
PHE A 106
 None
 1.24A 4kykA-3m2mA:
undetectable
4kykB-3m2mA:
undetectable		 4kykA-3m2mA:
21.74
4kykB-3m2mA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		4 / 5 HIS A  52
ASP A 125
GLY A 124
ASN A  46
 LAT  A 999 (-3.9A)
None
None
LAT  A 999 (-4.1A)
 1.41A 5x7pB-3m2mA:
undetectable		 5x7pB-3m2mA:
6.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		7 / 7 HIS A  44
ASN A  46
ARG A  48
ASN A  61
TRP A  68
GLU A  71
ARG A  73
 LAT  A 999 (-3.7A)
LAT  A 999 (-4.1A)
LAT  A 999 (-3.1A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.0A)
LAT  A 999 ( 4.7A)
 0.47A 6b8kA-3m2mA:
19.9		 6b8kA-3m2mA:
36.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_A_W9TA201_0
(GALECTIN-1)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		8 / 8 HIS A  44
ASN A  46
ARG A  48
HIS A  52
ASN A  61
TRP A  68
GLU A  71
ARG A  73
 LAT  A 999 (-3.7A)
LAT  A 999 (-4.1A)
LAT  A 999 (-3.1A)
LAT  A 999 (-3.9A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.0A)
LAT  A 999 ( 4.7A)
 0.33A 6b94A-3m2mA:
26.7		 6b94A-3m2mA:
92.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B94_B_W9TB201_0
(GALECTIN-1)		 3m2m GALECTIN-1
(Rattus
norvegicus) 		9 / 10 HIS A  44
ASN A  46
ARG A  48
HIS A  52
ASP A  54
ASN A  61
TRP A  68
GLU A  71
ARG A  73
 LAT  A 999 (-3.7A)
LAT  A 999 (-4.1A)
LAT  A 999 (-3.1A)
LAT  A 999 (-3.9A)
None
LAT  A 999 (-3.7A)
LAT  A 999 (-3.7A)
LAT  A 999 (-3.0A)
LAT  A 999 ( 4.7A)
 0.38A 6b94A-3m2mA:
26.7
6b94B-3m2mA:
25.9		 6b94A-3m2mA:
92.50
6b94B-3m2mA:
92.50