SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 8 HIS A  56
LEU A  15
ALA A  12
LEU A  11
 CL  A 224 (-4.3A)
None
None
None
 0.86A 1hwiD-3m33A:
undetectable		 1hwiD-3m33A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 ALA A  68
VAL A  49
TRP A  70
 None
 0.88A 1kqeA-3m33A:
undetectable
1kqeE-3m33A:
undetectable		 1kqeA-3m33A:
3.48
1kqeE-3m33A:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 ASP A 162
LEU A 211
LEU A 209
 None
 0.79A 1np1B-3m33A:
undetectable		 1np1B-3m33A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 LEU A  82
LEU A  79
SER A  76
 None
 0.62A 1tlmA-3m33A:
undetectable		 1tlmA-3m33A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 4 ASP A 162
LEU A 136
LEU A 211
LEU A 209
 None
 1.23A 1u18A-3m33A:
undetectable		 1u18A-3m33A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLY A  57
VAL A  92
ALA A  87
ASP A  59
ALA A  60
 None
None
None
GOL  A 233 (-3.3A)
None
 1.36A 2avdB-3m33A:
11.4		 2avdB-3m33A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 LEU A  43
LEU A  39
ASP A  91
ASP A  59
ALA A  60
 None
None
None
GOL  A 233 (-3.3A)
None
 1.17A 2br4E-3m33A:
8.8		 2br4E-3m33A:
25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 ASP A  36
ARG A 115
ASP A  59
ALA A  61
HIS A  56
 None
GOL  A 233 (-3.8A)
GOL  A 233 (-3.3A)
None
CL  A 224 (-4.3A)
 1.40A 2qmjA-3m33A:
undetectable		 2qmjA-3m33A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 5 TRP A  22
GLY A  16
GLY A  17
PHE A 182
 None
None
None
SO4  A 227 (-4.7A)
 1.05A 2qr2A-3m33A:
undetectable
2qr2B-3m33A:
undetectable		 2qr2A-3m33A:
20.31
2qr2B-3m33A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 4 ARG A 115
GLY A 139
GLU A  32
SER A 120
 GOL  A 233 (-3.8A)
None
None
SO4  A 228 (-2.5A)
 1.37A 2xctS-3m33A:
undetectable
2xctU-3m33A:
undetectable		 2xctS-3m33A:
16.42
2xctU-3m33A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 6 LEU A 111
PHE A 135
LEU A  39
PHE A  63
 None
 0.96A 3wg7P-3m33A:
undetectable
3wg7W-3m33A:
undetectable		 3wg7P-3m33A:
19.93
3wg7W-3m33A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 8 GLU A 205
ARG A 141
GLY A 139
ARG A 207
 SO4  A 230 ( 3.1A)
None
None
SO4  A 230 ( 3.9A)
 0.97A 4fgzA-3m33A:
12.4
4fgzB-3m33A:
12.6		 4fgzA-3m33A:
18.38
4fgzB-3m33A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 7 LEU A 105
ARG A  84
PRO A 118
SER A 120
 None
SO4  A 229 (-4.1A)
SO4  A 228 (-3.9A)
SO4  A 228 (-2.5A)
 1.27A 4klrA-3m33A:
2.3		 4klrA-3m33A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		3 / 3 PRO A 148
ASN A 143
HIS A 163
 None
 1.00A 4ma3H-3m33A:
undetectable
4ma3L-3m33A:
undetectable		 4ma3H-3m33A:
21.29
4ma3L-3m33A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 8 PHE A  75
GLU A  14
HIS A  56
THR A 119
 SO4  A 225 (-4.5A)
None
CL  A 224 (-4.3A)
SO4  A 228 (-3.4A)
 1.44A 5hqaA-3m33A:
undetectable		 5hqaA-3m33A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		4 / 5 LEU A 111
PHE A 135
LEU A  39
PHE A  63
 None
 1.18A 5x1fC-3m33A:
undetectable
5x1fJ-3m33A:
undetectable		 5x1fC-3m33A:
19.93
5x1fJ-3m33A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLY A  57
PRO A  65
GLY A  64
LEU A  82
ASP A  59
 None
None
None
None
GOL  A 233 (-3.3A)
 1.32A 5yn6A-3m33A:
undetectable		 5yn6A-3m33A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		6 / 12 PHE A 135
ILE A 122
LEU A 125
GLY A  53
ALA A  52
LEU A  50
 None
 1.10A 5zwrA-3m33A:
undetectable		 5zwrA-3m33A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3m33 UNCHARACTERIZED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 PHE A 135
ILE A 122
LEU A 125
ALA A  52
LEU A  50
 None
 1.11A 5zwrB-3m33A:
undetectable		 5zwrB-3m33A:
18.23