SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3m3m GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		3 / 3 SER A 156
TYR A 155
HIS A 154
 None
 0.54A 2r2vD-3m3mA:
undetectable		 2r2vD-3m3mA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3m3m GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 5 ALA A 164
GLU A 103
GLU A  98
ALA A 107
 None
GSH  A 209 ( 4.9A)
None
None
 1.40A 3r9tC-3m3mA:
undetectable		 3r9tC-3m3mA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3m3m GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 LEU A  81
VAL A  91
LEU A  56
LEU A  25
TYR A   2
 None
 1.49A 4o8fB-3m3mA:
undetectable		 4o8fB-3m3mA:
22.41