SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 LEU A  74
MET A   7
GLY A  51
LEU A  34
HIS A 170
 None
 1.35A 1brpA-3m3pA:
undetectable		 1brpA-3m3pA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 3 TRP A 228
ARG A 216
THR A 224
 None
 0.95A 1df7A-3m3pA:
undetectable		 1df7A-3m3pA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 4 VAL A 208
TRP A 113
TRP A 139
 None
 0.85A 1gmkA-3m3pA:
undetectable
1gmkB-3m3pA:
undetectable		 1gmkA-3m3pA:
10.37
1gmkB-3m3pA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 4 VAL A 208
TRP A 113
TRP A 139
 None
 0.97A 1gmkC-3m3pA:
undetectable
1gmkD-3m3pA:
undetectable		 1gmkC-3m3pA:
10.37
1gmkD-3m3pA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.41A 1jb0A-3m3pA:
undetectable		 1jb0A-3m3pA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 10 ILE A 222
PHE A  31
TYR A 233
GLU A 230
ARG A 227
 None
 1.17A 2piwA-3m3pA:
undetectable		 2piwA-3m3pA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 3 LEU A  42
PRO A  43
LEU A  74
 None
 0.50A 2qd5B-3m3pA:
undetectable		 2qd5B-3m3pA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 GLY A  87
HIS A 170
LEU A 166
SER A 145
GLY A 101
 None
 0.87A 2vmyA-3m3pA:
undetectable		 2vmyA-3m3pA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.25A 2wscA-3m3pA:
undetectable		 2wscA-3m3pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.25A 2wseA-3m3pA:
undetectable		 2wseA-3m3pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.24A 2wsfA-3m3pA:
undetectable		 2wsfA-3m3pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 8 GLU A 110
SER A 156
GLN A 162
CYH A  89
 None
 1.16A 3b9lA-3m3pA:
undetectable		 3b9lA-3m3pA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 8 GLU A 110
SER A 156
GLN A 162
VAL A 103
 None
 1.07A 3b9lA-3m3pA:
undetectable		 3b9lA-3m3pA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.26A 3lw5A-3m3pA:
undetectable		 3lw5A-3m3pA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 3 GLN A  93
THR A 143
LEU A 136
 None
 0.75A 3ondA-3m3pA:
3.5		 3ondA-3m3pA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.41A 3pcqA-3m3pA:
undetectable		 3pcqA-3m3pA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 5 GLU A 126
LEU A 125
HIS A 231
GLY A 129
 None
 0.81A 3pp1A-3m3pA:
undetectable		 3pp1A-3m3pA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 ALA A 229
LEU A 128
ALA A 163
ILE A 171
ILE A 153
 None
 1.13A 3ut5B-3m3pA:
undetectable		 3ut5B-3m3pA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 5 PHE A  23
TRP A 127
ILE A 153
TRP A 228
 None
 1.48A 3w37A-3m3pA:
0.0		 3w37A-3m3pA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 10 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.42A 4fe1A-3m3pA:
undetectable
4fe1J-3m3pA:
undetectable		 4fe1A-3m3pA:
15.42
4fe1J-3m3pA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 8 TYR A 233
ILE A  86
LEU A 240
GLY A 239
 None
 0.75A 4iqqD-3m3pA:
undetectable		 4iqqD-3m3pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 11 GLY A  56
GLY A  57
LEU A  90
HIS A 140
HIS A 176
 None
 0.46A 4l8fB-3m3pA:
15.8		 4l8fB-3m3pA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 11 GLY A  56
GLY A  57
LEU A  90
HIS A 140
HIS A 176
 None
 0.46A 4l8fD-3m3pA:
15.8		 4l8fD-3m3pA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 GLY A  87
LEU A 166
ILE A   9
MET A  55
ILE A 171
 None
 1.12A 4qtuB-3m3pA:
undetectable		 4qtuB-3m3pA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 7 PHE A 144
ILE A 146
GLY A 172
LEU A 128
 None
 0.94A 4zdzA-3m3pA:
undetectable		 4zdzA-3m3pA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 7 PHE A 144
ILE A 146
GLY A 172
LEU A 128
 None
 0.91A 4ze3A-3m3pA:
undetectable		 4ze3A-3m3pA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 PRO A  43
ALA A  44
ILE A   9
LEU A  52
ALA A  80
 None
 1.25A 5bw4B-3m3pA:
undetectable		 5bw4B-3m3pA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 12 GLU A 133
PHE A 144
ILE A 146
GLY A 172
LEU A 128
 None
 1.25A 5esgA-3m3pA:
undetectable		 5esgA-3m3pA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 9 MET A  36
PHE A  11
ALA A  61
LEU A  90
GLY A  57
 None
 1.38A 5l8rA-3m3pA:
undetectable		 5l8rA-3m3pA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		3 / 3 TYR A 233
HIS A  19
MET A 179
 None
 1.23A 6af6A-3m3pA:
undetectable		 6af6A-3m3pA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		4 / 5 HIS A 140
GLU A 178
LEU A 128
VAL A 232
 None
 1.13A 6bc9A-3m3pA:
undetectable		 6bc9A-3m3pA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3m3p GLUTAMINE AMIDO
TRANSFERASE
(Methylobacillus
flagellatus) 		5 / 10 ASP A  64
GLY A 100
ALA A 150
ASN A  62
VAL A 103
 None
 1.46A 6hu9L-3m3pA:
undetectable
6hu9P-3m3pA:
undetectable
6hu9T-3m3pA:
undetectable		 6hu9L-3m3pA:
20.23
6hu9P-3m3pA:
22.71
6hu9T-3m3pA:
11.55