SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		3 / 3 ARG A  99
GLY A 104
PRO A 105
 None
 0.73A 2hreD-3m3wA:
undetectable		 2hreD-3m3wA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		4 / 6 ALA A  58
ASP A  59
GLU A  89
ARG A  90
 None
 1.41A 2ouzA-3m3wA:
undetectable		 2ouzA-3m3wA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		4 / 4 GLY A  71
VAL A  68
GLY A  75
THR A  76
 None
 0.85A 3ib2A-3m3wA:
undetectable		 3ib2A-3m3wA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		3 / 4 ARG A  34
GLY A  32
GLU A  30
 None
 0.55A 4z2dB-3m3wA:
0.6
4z2dC-3m3wA:
undetectable		 4z2dB-3m3wA:
21.58
4z2dC-3m3wA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		3 / 3 GLU A  50
HIS A  95
ASP A 254
 None
 0.86A 5c0oG-3m3wA:
undetectable		 5c0oG-3m3wA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		4 / 6 ASP A  38
ARG A  34
GLY A  32
GLU A  30
 None
 0.56A 5cdqA-3m3wA:
2.8
5cdqC-3m3wA:
2.8
5cdqD-3m3wA:
undetectable		 5cdqA-3m3wA:
22.24
5cdqC-3m3wA:
22.24
5cdqD-3m3wA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 3m3w PROTEIN KINASE C AND
CASEIN KINASE II
SUBSTRATE PROTEIN 3
(Mus
musculus) 		5 / 12 HIS A 250
SER A 257
SER A 258
HIS A 252
LEU A 247
 None
 1.25A 6chgC-3m3wA:
undetectable		 6chgC-3m3wA:
19.03