SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMI_A_BHSA1610_1 (NITRIC OXIDE SYNTHASE)	3m45	CELL ADHESION MOLECULE 2 (Mus musculus)	4 / 8	VAL A 129 ARG A 85 ALA A 49 GLU A 108	None	1.04A	1dmiA-3m45A: undetectable 1dmiB-3m45A: undetectable	1dmiA-3m45A: 14.73 1dmiB-3m45A: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN5_A_FUNA1356_2 (THYROXINE-BINDING GLOBULIN)	3m45	CELL ADHESION MOLECULE 2 (Mus musculus)	3 / 3	LEU A 88 ARG A 90 ILE A 98	None	0.68A	2xn5B-3m45A: undetectable	2xn5B-3m45A: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB504_0 (FERROCHELATASE, MITOCHONDRIAL)	3m45	CELL ADHESION MOLECULE 2 (Mus musculus)	3 / 3	LEU A 81 ILE A 86 ARG A 85	None	0.55A	4mk4B-3m45A: undetectable	4mk4B-3m45A: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XNX_A_41XA707_1 (TRANSPORTER)	3m45	CELL ADHESION MOLECULE 2 (Mus musculus)	5 / 11	ALA A 49 VAL A 100 GLY A 109 VAL A 129 SER A 104	None	1.17A	4xnxA-3m45A: undetectable	4xnxA-3m45A: 12.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DMI_A_BHSA1610_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","3m45","CELL ADHESION MOLECULE 2","Mus musculus",4,"VAL A 129;ARG A  85;ALA A  49;GLU A 108","None","1.04A","1dmiA-3m45A:undetectable;1dmiB-3m45A:undetectable","1dmiA-3m45A:14.73;1dmiB-3m45A:14.73"],["2XN5_A_FUNA1356_2","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","3m45","CELL ADHESION MOLECULE 2","Mus musculus",3,"LEU A  88;ARG A  90;ILE A  98","None","0.68A","2xn5B-3m45A:undetectable","2xn5B-3m45A:11.70"],["4MK4_B_CHDB504_0","FERROCHELATASE, MITOCHONDRIAL","3m45","CELL ADHESION MOLECULE 2","Mus musculus",3,"LEU A  81;ILE A  86;ARG A  85","None","0.55A","4mk4B-3m45A:undetectable","4mk4B-3m45A:14.17"],["4XNX_A_41XA707_1","TRANSPORTER","3m45","CELL ADHESION MOLECULE 2","Mus musculus",5,"ALA A  49;VAL A 100;GLY A 109;VAL A 129;SER A 104","None","1.17A","4xnxA-3m45A:undetectable","4xnxA-3m45A:12.00"]]