SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
0.98A 3d1zA-3m4rA:
undetectable
3d1zA-3m4rA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
4 / 8 VAL A  31
GLY A  25
ILE A  67
GLY A  35
None
0.82A 3n9jB-3m4rA:
undetectable
3n9jB-3m4rA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
1.03A 3nu3A-3m4rA:
undetectable
3nu3A-3m4rA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 10 LEU A 188
ILE A 202
GLY A  25
SER A  39
VAL A 125
None
1.02A 3ogpA-3m4rA:
undetectable
3ogpA-3m4rA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A  20
ILE A  24
GLY A 194
PHE A 124
MET A 126
None
1.17A 3ps9A-3m4rA:
undetectable
3ps9A-3m4rA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 PHE A  72
ILE A  24
GLY A 194
PHE A 124
MET A 126
None
1.32A 3ps9A-3m4rA:
undetectable
3ps9A-3m4rA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
1.00A 4jecB-3m4rA:
undetectable
4jecB-3m4rA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
1.09A 4njvA-3m4rA:
undetectable
4njvA-3m4rA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 ASP A 178
LEU A 187
ARG A 200
ILE A 204
MET A   1
None
1.13A 4x1fA-3m4rA:
undetectable
4x1fA-3m4rA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 ASP A 178
LEU A 187
ARG A 200
ILE A 204
MET A   1
None
1.11A 4x1gA-3m4rA:
undetectable
4x1gA-3m4rA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
4 / 7 SER A 111
HIS A 129
GLY A  35
LEU A 116
None
ZN  A 220 (-3.3A)
None
None
0.81A 6btxA-3m4rA:
undetectable
6btxA-3m4rA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
1.04A 6dh0B-3m4rA:
undetectable
6dh0B-3m4rA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)
3m4r UNCHARACTERIZED
PROTEIN

(Thermoplasma
acidophilum)
5 / 12 GLY A 191
ALA A 197
ASP A 199
GLY A 179
ILE A 180
None
1.02A 6dh3B-3m4rA:
undetectable
6dh3B-3m4rA:
17.35