SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m4x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 TRP A 153
ALA A 391
VAL A 155
 None
 0.92A 1c4dA-3m4xA:
undetectable
1c4dB-3m4xA:
undetectable		 1c4dA-3m4xA:
5.81
1c4dB-3m4xA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 SER A 205
THR A 202
PHE A 191
GLY A 187
 None
 1.05A 1icuA-3m4xA:
undetectable
1icuB-3m4xA:
undetectable		 1icuA-3m4xA:
19.49
1icuB-3m4xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 PHE A 191
GLY A 187
SER A 205
THR A 202
 None
 1.01A 1icuA-3m4xA:
undetectable
1icuB-3m4xA:
undetectable		 1icuA-3m4xA:
19.49
1icuB-3m4xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 SER A 205
THR A 202
PHE A 191
GLY A 187
 None
 1.00A 1icuC-3m4xA:
undetectable
1icuD-3m4xA:
undetectable		 1icuC-3m4xA:
19.49
1icuD-3m4xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 5 PHE A 191
GLY A 187
SER A 205
THR A 202
 None
 1.03A 1icuC-3m4xA:
undetectable
1icuD-3m4xA:
undetectable		 1icuC-3m4xA:
19.49
1icuD-3m4xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 5 PHE A 191
GLY A 187
SER A 205
THR A 202
 None
 1.00A 1icvA-3m4xA:
undetectable
1icvB-3m4xA:
undetectable		 1icvA-3m4xA:
19.49
1icvB-3m4xA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 TYR A  86
GLY A 154
ALA A 391
GLY A 436
LEU A 427
 None
 1.02A 1igxA-3m4xA:
undetectable		 1igxA-3m4xA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 SER A 205
THR A 202
PHE A 191
GLY A 187
 None
 1.10A 1kqbA-3m4xA:
undetectable
1kqbB-3m4xA:
undetectable		 1kqbA-3m4xA:
22.44
1kqbB-3m4xA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 SER A 205
THR A 202
PHE A 191
GLY A 187
 None
 1.09A 1kqbC-3m4xA:
undetectable
1kqbD-3m4xA:
undetectable		 1kqbC-3m4xA:
22.44
1kqbD-3m4xA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 PHE A 191
GLY A 187
SER A 205
THR A 202
 None
 1.14A 1kqbC-3m4xA:
undetectable
1kqbD-3m4xA:
undetectable		 1kqbC-3m4xA:
22.44
1kqbD-3m4xA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ARG A 152
VAL A 155
TRP A 153
 None
 0.69A 1qw6A-3m4xA:
undetectable		 1qw6A-3m4xA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ARG A 152
VAL A 155
TRP A 153
 None
 0.67A 1qwcA-3m4xA:
undetectable		 1qwcA-3m4xA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		7 / 12 CYH A 113
ALA A 115
GLY A 117
GLY A 118
LYS A 119
ILE A 138
PRO A 184
 None
 0.45A 1sqfA-3m4xA:
31.2		 1sqfA-3m4xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ALA A 387
VAL A 155
TRP A 153
 None
 0.81A 1tkqB-3m4xA:
undetectable		 1tkqB-3m4xA:
5.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ARG A 152
VAL A 155
TRP A 153
 None
 0.71A 1vagA-3m4xA:
undetectable		 1vagA-3m4xA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ARG A 152
VAL A 155
TRP A 153
 None
 0.75A 1zviA-3m4xA:
undetectable		 1zviA-3m4xA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 8 PHE A 175
LEU A 132
LEU A 362
LEU A 365
 None
 0.96A 2bfpA-3m4xA:
5.4		 2bfpA-3m4xA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 8 PHE A 175
LEU A 132
LEU A 362
LEU A 365
 None
 1.00A 2bfpB-3m4xA:
6.1		 2bfpB-3m4xA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 4 VAL A  97
LEU A 146
ILE A 150
LEU A 133
 None
 1.05A 2byoA-3m4xA:
undetectable		 2byoA-3m4xA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 HIS A  82
ARG A 152
PHE A 449
PRO A 450
 None
 1.02A 2qqtA-3m4xA:
undetectable		 2qqtA-3m4xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 8 GLY A  70
ILE A 285
VAL A  36
SER A  67
 None
 0.85A 2yoeB-3m4xA:
undetectable
2yoeC-3m4xA:
undetectable		 2yoeB-3m4xA:
20.59
2yoeC-3m4xA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 HIS A  82
ARG A 152
PHE A 449
PRO A 450
 None
 1.07A 3gclA-3m4xA:
undetectable		 3gclA-3m4xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 GLY A  70
PRO A  92
LEU A  72
 None
 0.56A 3hcpB-3m4xA:
undetectable		 3hcpB-3m4xA:
20.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		7 / 12 PRO A 116
GLY A 117
GLY A 118
LYS A 119
PRO A 165
ASP A 182
PRO A 184
 None
 0.48A 3m6vA-3m4xA:
47.8		 3m6vA-3m4xA:
40.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		7 / 12 PRO A 116
GLY A 117
GLY A 118
LYS A 119
PRO A 165
ASP A 182
PRO A 184
 None
 0.52A 3m6vB-3m4xA:
47.7		 3m6vB-3m4xA:
40.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		6 / 12 PRO A 116
GLY A 117
GLY A 118
LYS A 119
PRO A 165
PRO A 184
 None
 0.46A 3m6wA-3m4xA:
47.2		 3m6wA-3m4xA:
40.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 7 HIS A  82
ARG A 152
PHE A 449
PRO A 450
 None
 1.08A 3ql6A-3m4xA:
undetectable		 3ql6A-3m4xA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 GLN A  83
ALA A  84
ILE A 395
LEU A 428
VAL A 429
 None
 1.23A 4azsA-3m4xA:
8.0		 4azsA-3m4xA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 PHE A 417
GLY A 438
LEU A 401
VAL A 426
 None
 0.92A 4dubA-3m4xA:
undetectable		 4dubA-3m4xA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 PHE A 417
GLY A 438
LEU A 401
VAL A 426
 None
 0.90A 4dubB-3m4xA:
undetectable		 4dubB-3m4xA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		8 / 12 CYH A 113
PRO A 116
GLY A 117
GLY A 118
LYS A 119
ASN A 136
ASP A 182
PRO A 184
 None
 0.41A 4fp9A-3m4xA:
27.8		 4fp9A-3m4xA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		8 / 12 CYH A 113
PRO A 116
GLY A 117
GLY A 118
LYS A 119
ASN A 136
ASP A 182
PRO A 184
 None
 0.42A 4fp9C-3m4xA:
27.7		 4fp9C-3m4xA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		7 / 12 CYH A 113
PRO A 116
GLY A 117
GLY A 118
LYS A 119
ASN A 136
PRO A 184
 None
 0.34A 4fp9D-3m4xA:
27.8		 4fp9D-3m4xA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		8 / 12 CYH A 113
PRO A 116
GLY A 117
GLY A 118
LYS A 119
ASN A 136
ASP A 182
PRO A 184
 None
 0.43A 4fp9F-3m4xA:
27.7		 4fp9F-3m4xA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		7 / 12 CYH A 113
PRO A 116
GLY A 117
GLY A 118
LYS A 119
ASN A 136
PRO A 184
 None
 0.34A 4fzvA-3m4xA:
27.7		 4fzvA-3m4xA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 8 ASN A 136
CYH A 113
GLU A 137
GLU A 167
 None
 1.06A 4gkhD-3m4xA:
0.9		 4gkhD-3m4xA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 ALA A 298
LEU A 230
LEU A 249
ILE A 216
THR A 282
 None
 1.01A 4ky8C-3m4xA:
undetectable		 4ky8C-3m4xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		3 / 3 ARG A 152
VAL A 155
TRP A 153
 None
 0.74A 5fvoA-3m4xA:
undetectable		 5fvoA-3m4xA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 LEU A 372
ASP A 376
GLY A 375
LEU A 345
ALA A 341
 None
 1.38A 5kc4E-3m4xA:
undetectable		 5kc4E-3m4xA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 GLY A 118
GLN A  90
VAL A 180
ALA A 124
LEU A 123
 None
 1.02A 5kocA-3m4xA:
10.5		 5kocA-3m4xA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 CYH A 113
ALA A 115
PRO A 116
GLY A 118
ASP A 182
 None
 0.47A 5wwsA-3m4xA:
32.5		 5wwsA-3m4xA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		6 / 12 CYH A 113
ALA A 115
PRO A 116
GLY A 118
LYS A 119
ASP A 182
 None
 0.52A 5wwsB-3m4xA:
32.5		 5wwsB-3m4xA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 12 LEU A 217
ILE A 221
LEU A 262
GLY A 228
LEU A 300
 None
 1.23A 6a7pA-3m4xA:
undetectable		 6a7pA-3m4xA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 6 ILE A 150
LEU A 133
VAL A 160
SER A 120
 None
 1.27A 6f6jA-3m4xA:
undetectable		 6f6jA-3m4xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 7 LEU A 401
TYR A 411
VAL A 426
TRP A 425
 None
 1.38A 6g2pA-3m4xA:
1.8		 6g2pA-3m4xA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		5 / 10 LEU A 401
LEU A 428
TYR A 411
VAL A 426
TRP A 425
 None
 1.33A 6g2pB-3m4xA:
1.8		 6g2pB-3m4xA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3m4x NOL1/NOP2/SUN FAMILY
PROTEIN
(Enterococcus
faecium) 		4 / 7 GLY A  73
THR A  74
PHE A  40
HIS A  57
 None
 0.93A 6jnhA-3m4xA:
3.1		 6jnhA-3m4xA:
17.63