SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)
3m51 14-3-3-LIKE PROTEIN
C

(Nicotiana
tabacum)
5 / 12 THR A 167
ALA A 165
THR A 154
LEU A 155
LEU A 200
None
1.13A 1eiiA-3m51A:
undetectable
1eiiA-3m51A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)
3m51 14-3-3-LIKE PROTEIN
C

(Nicotiana
tabacum)
3 / 3 LYS A 220
THR A 224
ILE A 209
None
0.69A 4e0fB-3m51A:
undetectable
4e0fB-3m51A:
25.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)
3m51 14-3-3-LIKE PROTEIN
C

(Nicotiana
tabacum)
4 / 5 PHE A 205
ILE A 209
MET A 227
GLN A 228
None
0.43A 5jm4A-3m51A:
30.9
5jm4A-3m51A:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M35_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)
3m51 14-3-3-LIKE PROTEIN
C

(Nicotiana
tabacum)
4 / 5 PHE A 205
THR A 224
MET A 227
GLN A 228
None
0.64A 5m35A-3m51A:
31.6
5m35A-3m51A:
64.02