SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3m5h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 LEU A 235
LEU A 177
ALA A 176
PHE A 232
ILE A 179
 None
 1.10A 1g5yC-3m5hA:
undetectable		 1g5yC-3m5hA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 PHE A  82
LEU A  61
ILE A  88
SER A  84
 None
 1.18A 1sbrA-3m5hA:
undetectable
1sbrB-3m5hA:
undetectable		 1sbrA-3m5hA:
19.69
1sbrB-3m5hA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 PHE A 245
LEU A 235
PHE A 125
MET A 123
 None
 1.37A 1wrkB-3m5hA:
undetectable		 1wrkB-3m5hA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 ARG A 109
ASP A  95
ILE A  96
GLU A 105
 None
 1.46A 2xrzA-3m5hA:
undetectable
2xrzB-3m5hA:
undetectable		 2xrzA-3m5hA:
19.16
2xrzB-3m5hA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 LEU A  66
LEU A 108
PHE A  82
ILE A 118
GLY A 116
 None
 1.20A 3kk6B-3m5hA:
undetectable		 3kk6B-3m5hA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 PHE A  82
SER A 265
SER A 115
 None
 1.02A 3ufgB-3m5hA:
undetectable		 3ufgB-3m5hA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 PRO A  74
ARG A 141
GLY A 144
ALA A 138
 None
 1.10A 4g0uA-3m5hA:
undetectable		 4g0uA-3m5hA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 GLN A 269
GLY A 267
ILE A  51
ASP A  85
 None
 1.00A 5vlmH-3m5hA:
undetectable		 5vlmH-3m5hA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 THR A  69
GLY A  68
GLY A  65
LEU A  61
 None
 0.74A 5vw5A-3m5hA:
undetectable		 5vw5A-3m5hA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3m5h HEMAGGLUTININ
(Influenza
A
virus) 		5 / 9 ILE A  88
GLY A 267
LEU A 266
GLY A 117
ARG A  90
 None
 1.32A 6nm4B-3m5hA:
undetectable		 6nm4B-3m5hA:
19.38